异常子宫出血患者子宫内膜病理类型与临床特征的关系  

Relationship between Pathologic Type of Endometrium and Its Clinical Features in Patients with Abnormal Uterus Bleeding

作　　者：李淑娟[1] 王爱芹[1] 杨学军[1] 常子强[1] LI Shu-juan;WANG Ai-qin;YANG Xue-jun;CHANG Zi-qiang(Department of Gynecology,Shunyi District Hospital,Beijing 101300,China)

机构地区：[1]北京市顺义区医院妇科

出　　处：《医学信息》2019年第14期104-106,共3页Journal of Medical Information

摘　　要：目的探讨异常子宫出血患者子宫内膜病理类型与患者年龄、肥胖、高血压、血糖异常及高脂血症的关系。方法收集2018年1月1日~12月31日在我院因异常子宫出血进行宫腔镜手术和诊刮的符合条件的277例患者的临床资料,包括子宫内膜病理结果、年龄、身高、体质量、血糖、血脂、血压等,计算异常子宫出血患者中子宫内膜病理类型的构成比,分析不同病理结果与患者年龄、肥胖、血压、血糖及血脂的关系。结果①子宫内膜病理类型包括正常子宫内膜、子宫内膜息肉、子宫内膜增生不伴非典型性、子宫内膜增生伴非典型性及子宫内膜癌的构成比分别为23.10%、25.27%、42.24%、6.49%和2.88%;②子宫内膜癌患者平均年龄(54.87±3.35)岁,大于正常子宫内膜患者的平均年龄(36.29±3.27)岁,统计学意义显著(P<0.01);③子宫内膜增生伴非典型性患者及子宫内膜癌患者肥胖的高血压、血糖异常及高血脂发生情况与正常子宫内膜患者比较,差异有统计学意义(P<0.05)。结论异常子宫出血患者近一半人群存在子宫内膜增生,个别患者甚至出现癌变,与肥胖、高血压、高血脂及血糖异常有一定联系,提示子宫内膜病变可能与代谢性疾病相关。建议患者尽早改变生活方式,合理饮食及运动以改善机体的代谢,则有可能在很大程度上预防子宫内膜癌的发生。Objective To investigate the relationship between endometrial pathological types of patients with abnormal uterus bleeding and age,obesity, hypertension, abnormal blood glucose and hyperlipidemia. Methods The clinical data of 277 patients who underwent hysteroscopic surgery and diagnosis of uterus bleeding due to abnormal uterus bleeding from January 1 to December 31, 2018, including endometrial pathological results,age, height, body mass, blood glucose, blood lipids, blood pressure, etc., to calculate the composition ratio of endometrial pathological types in patients with abnormal uterus bleeding, and to analyze the relationship between different pathological results and factors such as age, obesity, blood pressure,blood sugar and blood lipids. Results (1) Endometrial pathological types including normal endometrium, endometrial polyps, endometrial hyperplasia without atypical, endometrial hyperplasia with atypical and endometrial cancer, the composition ratio was respectively 23.10%, 25.27 %, 42.24%,6.49%, and 2.88%;(2) Me age of endometrial cancer patients(54.87 ±3.35) years old, greater than the average age of normal endometrial patients(36.29 ±3.27) years, with stically significant(P <0.01);(3) Eometrial hyperplasia with atypical patients, endometrial cancer patients with obesity,hypertension, abnormal blood glucose and high blood lipids compared with normal endometrial patients, the difference was statistically significant( P<0.05).Conclusion Endometrial hyperplasia exists in nearly half of patients with abnormal uterus bleeding. Individual patients may even develop cancer, which is associated with obesity, hypertension, hyperlipidemia and abnormal blood glucose, suggesting that endometrial lesions may be associated with metabolic diseases. It is recommended that patients change their lifestyle as early as possible, and proper diet and exercise to improve the body’s metabolism may prevent endometrial cancer to a large extent.

关 键 词：异常子宫出血 子宫内膜病理 肥胖 代谢综合征 

分 类 号：R711[医药卫生—妇产科学]