5-羟色胺对围产期母羊生产性能及血浆和乳中钙转运相关生化指标的影响  

Effects of Serotonin on Performance and Plasma and Milk Calcium Transport Related Biochemical Index of Perinatal Ewes

作　　者：桑丹 娜美日嘎[1,2] 孙海洲 金鹿[2] 张崇志[2] 李胜利[2] 王双锁[3] 刘拥军 敖长金 SANG Dan;NAMIRGA;SUN Haizhou;JIN Lu;ZHANG Chongzhi;LI Shengli;WANG Shuangsuo;LIU Yongjun;AO Changjin(College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;Animal Nutrition and Feed Research Institution of Inner Mongolia Academy of Agriculture and Animal Husbandry Academy, Hohhot 010031, China;Urat Front Banner Livestock Improvement Station, Bayannur 014400, China)

机构地区：[1]内蒙古农业大学动物科学学院,呼和浩特010018 [2]内蒙古农牧业科学院动物营养与饲料研究所,呼和浩特010031 [3]乌拉特前旗家畜改良工作站,巴彦淖尔014400

出　　处：《动物营养学报》2019年第7期3174-3180,共7页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：内蒙古农牧业科技创新基金项目(2018CXJJM04);国家绒毛用羊产业技术体系(CARS-39-11);内蒙古自然科学博士(联合)基金(2016BS(LH)0304)

摘　　要：本试验旨在研究5-羟色胺(5-HT)对围产期母羊生产性能及血浆和乳中钙转运相关生化指标的影响。试验选用30只巴美肉羊母羊,按体重随机分为3组,分别为对照组、5-羟基色胺酸(5-HTP)组(灌注5-HTP)和色氨酸(Trp)组(灌注Trp),每组10只。在母羊围产期产前第7天至产后第0天,进行颈静脉灌注,5-HTP和Trp的灌注剂量均为0.178 mg/kg BW,浓度为0.1 mg/mL;对照组灌注同等剂量的生理盐水。试验期为产前第7天至产后第30天。结果表明:1)各组间母羊体重无显著差异(P>0.05)。产后第5、9和15天,Trp组母羊泌乳量均低于对照组(P>0.05);产后第9和15天,5-HTP组母羊泌乳量均高于对照组(P>0.05)。产后第16~30天,5-HTP组羔羊平均日增重显著高于对照组(P<0.05)。2)产后第15天,Trp组血浆和乳中钙浓度显著高于对照组(P<0.05);产后第3、6和15天,5-HTP组血浆和乳中钙浓度显著高于对照组(P<0.05)。产后第6天,Trp组血浆5-HT浓度显著高于对照组(P<0.05);产后第30天,Trp组乳中5-HT浓度显著高于对照组(P<0.05);产后第6、9和30天,5-HTP组血浆和乳中5-HT浓度显著高于对照组(P<0.05)。产后第3、6和15天,Trp组和5-HTP组血浆甲状旁腺素相关蛋白(PTHrP)浓度均显著高于对照组(P<0.05)。由此可见,灌注5-HTP可以促进母羊泌乳,提高羊羔平均日增重;灌注5-HTP和Trp可以增加血浆和乳中钙、5-HT浓度及血浆PTHrP浓度。This experiment was conducted to investigate effects of serotonin(5-HT)on performance and plasma and milk calcium transport related biochemical index of perinatal ewes.Thirty Bamei ewes with similar body weight were randomly allotted 3 groups,which were control group,5-hydroxy-tryptophan(5-HTP)group(perfused 5-HTP)and tryptophan(Trp)group(perfused Trp),respectively,each group contained 10 ewes.Ewes jugular vein perfusion was conducted from prenatal day 7 to postpartum day 0,the perfusion dose of 5-HTP and Trp was 0.178 mg/kg BW,and the concentration was 0.1 mg/mL;the control group was perfused with the same dose of saline.The experiment lasted form prenatal day 7 to postpartum day 30.The results showed as follows:1)there was no significant difference in body weight of ewes among all groups(P>0.05).On postpartum day 5,9 and 15,the milk yield of ewes in Trp group was lower than that in the control group(P>0.05);on postpartum day 9 and 15,the milk yield of ewes in 5-HTP group was higher than that in the control group(P>0.05).On postpartum day 16 to 30,the average daily gain of lambs in 5-HTP group was significantly higher than that in the control group(P<0.05).2)On postpartum day 15,the plasma and milk calcium concentration in Trp group was significantly higher than that in the control group(P<0.05);on postpartum day 3,6 and 15,the plasma and milk calcium concentration in 5-HTP group was significantly higher than that in the control group(P<0.05).On postpartum day 6,the plasma 5-HT concentration in Trp group was significantly higher than that in the control group(P<0.05);on postpartum day 30,the milk 5-HT concentration in Trp group was significantly higher than that in the control group(P<0.05);on postpartum day 6,9 and 30,the plasma and milk 5-HT concentration in 5-HTP group was significantly higher than that in the control group(P<0.05).On postpartum day 3,6 and 15,the plasma parathyroid hormone-related protein(PTHrP)concentration in Trp group and 5-HTP group was significantly higher than that in the control group

关 键 词：5-羟色胺 泌乳 平均日增重 血钙 乳钙 母羊 

分 类 号：S826[农业科学—畜牧学]