老年颅脑腔隙灶改变危险因素及与尿微量白蛋的相关性  

Risk Factors of Senile Craniocerebral Cavity Changes and Its Correlation with Urine Microalbumin

作　　者：邱钦圣 许团新[2] QIU Qin-sheng;XU Tuan-xin(Department of Radiology, Dongguan Daojiao Hospital, Dongguan, Guangdong Province, 523000 China;Department of Radiology, Dongguan Donghua Hospital, Dongguan, Guangdong Province, 523000 China)

机构地区：[1]东莞市道滘医院放射科,广东东莞523000 [2]东莞东华医院放射科,广东东莞523000

出　　处：《中外医疗》2019年第15期178-180,共3页China & Foreign Medical Treatment

摘　　要：目的探讨老年颅脑腔隙灶改变的危险因素及与尿微量蛋白的相关性,为该病临床诊治提供依据参考。方法以2017年1月-2018年12月为时限,方便择取该院及东莞东华医院颅脑MR检查可见腔隙灶改变的34例老年患者为实验组,另择取该院及东莞东华医院同期34例颅脑MR示正常的老年健康志愿者为对照组,对比观察两组尿微量蛋白蛋水平,收集两组临床资料,Logistic回归分析导致老年颅脑MR腔隙灶改变的危险因素。结果实验组高血压病史85.29%、糖尿病史44.44%,血脂异常64.71%,吸烟史44.11%,饮酒史55.88%,尿微量白蛋白(23.46±0.82)mg/L,均高于对照组(χ^2=10.713,5.682,7.335,4.923,3.268,t=6.293;P<0.05),Logistic示是老年颅脑MR腔隙灶改变独立危险因素。结论尿微量白蛋白水平升高是老年颅脑MR腔隙灶改变的独立危险因素,此外也受高血压、糖尿病与吸烟的影响,应引起临床重视,重点加强防治。Objective To investigate the risk factors of cerebral ventricle changes in the elderly and its correlation with microalbuminuria,and provide evidence for clinical diagnosis and treatment of this disease.Methods From January 2017 to December 2018,34 elderly patients with changes in luminal lesions in our hospital and Donghua Hospital of Dongguan were convenient chosen as experimental group.At the same time,34 elderly healthy volunteers in Donghua Hospital with normal brain MR showed the control group.The urine microalbumin levels were compared between the two groups.The clinical data of the two groups were collected.Logistic regression analysis showed the risk factors of MR lesions in the elderly.Results The experimental group had a history of hypertension of 85.29%,a history of diabetes of 44.44%,a dyslipidemia of 64.71%,a history of smoking of 44.11%,a drinking history of 55.88%,and a urine microalbumin (23.46±0.82) mg/L,which were higher than the control group (χ^2=10.713,5.682,7.335,4.923,3.268,t=6.293;P<0.05),Logistic showed an independent risk factor for MR luminal changes in elderly patients.Conclusion The increase of urinary microalbumin is an independent risk factor for the changes of MR lesions in elderly patients.In addition,it is also affected by hypertension,diabetes and smoking.It should be given clinical attention and focus on strengthening prevention and treatment.

关 键 词：头颅MR 腔隙灶改变 尿微量白蛋白 危险因素 

分 类 号：R5[医药卫生—内科学]