脑微出血致认知障碍患者颅脑MRI表现特点分析  

MRI Features of Brain in Patients with Cognitive Disorders Caused by Cerebral Microbleeds

作　　者：陆练军[1] 魏丽 周悦 尹榕 LU Lian-jun;WEI Li;ZHOU Yue(Department of Neurology,Shanghai Pudong New Area People' s Hospital,Shanghai 201299,China)

机构地区：[1]上海市浦东新区人民医院神经内科,上海201299 [2]联勤保障部队第940医院神经内科,甘肃兰州730000

出　　处：《中国CT和MRI杂志》2019年第6期12-14,48,共4页Chinese Journal of CT and MRI

摘　　要：目的探究脑微出血(CMBs)在颅脑磁共振成像(MRI)上的影像表现,分析CMBs发生部位、数量与认知障碍的相关性。方法对入选患者行常规头颅MRI及SWI检查,选择CMBs阳性患者(CMBs组)52例和CMBs阴性患者54(对照组),比较CMBs组患者CMBs分区情况、两组患者MoCA评分差异及不同部位CMBs数量与蒙特利尔认知评估量表(MoCA)评分的相关性。结果共检出1657个CMBs病灶,SWI对CMBs病灶的检出数量较MRI常规序列更多,且以大脑半球深部及颞叶分布最多;与对照组比较,CMBs组MoCA各维度评分及总分均显著降低,差异有统计学意义(P<0.05);Spearman相关性分析显示,CMBs总数与MoCA评分负相关(r=-0.68,P<0.05)。结论SWI较常规MRI序列能检出更多CMBs病灶,且不同部位CMBs数量与患者认知障碍密切相关,CMBs数量越多,患者认知障碍越严重。Objective To investigate imaging findings of cerebral microbleeds (CMBs) on brain magnetic resonance imaging (MRI),and to analyze location and number of CMBs, and its correlation with cognitive disorders.Methods The routine brain MRI and SWI were performed on the chosen patients.52 patients with positive CMBs (CMBs group) and 54 patients with negative CMBs (control group) were selected.The CMBs partitions of patients were compared in CMBs group.The differences of MoCA scores,the correlation between CMBs quantity at different sites and the score of Montreal Cognitive Assessment (MoCA) were compared between the two groups.Results A total of 1657 CMBs lesions were detected.The detected number of CMBs lesions by SWI was more than that by MRI regular sequence.And deep cerebral hemisphere and temporal distribution were the most.Compared with those in the control group,the scores in each dimension and total scores of MoCA in the CMBs group were significantly lower (P<0.05).Spearman correlation analysis showed that the total number of CMBs was negatively correlated with MoCA score (r=-0.68,P<0.05).Conclusion Compared with routine MRI sequences, SWI can detect more CMBs lesions.And the number of CMBs at different sites is closely related to cognitive disorders of patients.The more number of CMBs,the more serious the cognitive disorders.

关 键 词：脑微出血 磁共振成像 认知障碍 

分 类 号：R722.151[医药卫生—儿科]