中央型和周围型鳞癌患者临床特点及CT影像学特征研究  

Study on the Clinical Characteristics and CT Imaging Features in Patients with Central and Peripheral Squamous Cell Carcinoma

作　　者：姜博[1] 王建 曾小松[1] JIANG Bo;WANG Jian;ZENG Xiao-song(Department of CT/MRI Room, Suzhou municipal hospital, Suzhou 234000, Anhui Province, China)

机构地区：[1]安徽省宿州市立医院CT/MR室

出　　处：《中国CT和MRI杂志》2019年第7期67-70,共4页Chinese Journal of CT and MRI

摘　　要：目的研究分析中央型和周围型鳞癌患者临床特点以及CT影像学特征研究。方法选取2013年1月至2018年6月在我院经病理证实的42例肺鳞癌患者作为研究对象,按照病理结果进行分组,其中病理结果为中央型肺鳞癌的22例患者作为中央型肺鳞癌组,结果为周围型肺鳞癌的20例患者作为周围型肺鳞癌组,比较并分析两组患者临床特点以及CT影像学特征。结果两组患者男性患者数明显高于女性,中央型肺鳞癌组患者年龄处于≥45岁和≤60岁的人数明显多于>60岁的患者,周围型肺鳞癌组患者年龄>60岁的患者明显多于年龄处于≥45岁和≤60岁的人数,两组患者具有吸烟史患者数明显高于不具有吸烟史患者,中央型肺鳞癌患者吸烟率明显高于周围型肺鳞癌患者,差异具有统计学意义(P<0.05)。比较两组患者的肿瘤大小以及分期情况,差异具有统计学意义(P<0.05),中央型肺鳞癌组肿瘤大小明显大于周围型肺鳞癌组,差异不具有统计学意义(P>0.05),中央型肺鳞癌组患者分化情况明显差于周围型肺鳞癌组患者,差异具有统计学意义(P<0.05)。中央型肺鳞癌组患者咳嗽、咯血、咳痰、痰中带血、胸痛、胸闷、气喘、转移症状、刺激性干咳、发热、无症状以及其他临床症状特点明显多于周围型肺鳞癌组患者,差异具有统计学意义(P<0.05)。中央型肺鳞癌CT影像学特征以支气管狭窄、肿块为主,周围型肺鳞癌CT影像学特征以结节、分叶征、毛刺征为主。结论中央型肺鳞癌与周围型肺鳞癌的主要临床特点是咳嗽、咯血、咳痰、胸痛、胸闷、发热,中央型肺鳞癌CT影像学特征以支气管狭窄、肿块为主,周围型肺鳞癌CT影像学特征以结节、分叶征、毛刺征为主。Objective To analyze the clinicalcharacteristics and CT imaging features in patients with central and peripheral squamous cell carcinoma. Methods 42 patients with lung squamous cell carcinoma confirmed by pathology in our hospital between January2013 and June 2017 were divided into as the central lung squamous cell carcinoma group(n=22, patients with central lung squamous cell carcinoma) and peripheral lung squamous cell carcinoma(n=20, patients with peripheral lung squamous cell carcinoma) according to the biopsy results.The clinicalcharacteristics and CT imaging features of two groups were compared and analyzed. Results The number of male patients in the two groups was significantly higher than that of female patients. The patients of ≥45 years old and≤60 years old in the central lung squamous cell carcinoma group were significantly more than those of >60 years old, vice versa in the peripheral lung squamous cell carcinoma group. The number of patients with smoking history in the two groups was significantly higher than that in patients without smoking history;the smoking rate of patients with central lung squamous cell carcinoma was significantly higher than that of peripheral lung squamous cell carcinoma(P<0.05). The tumor size and staging of the two groups were statistically significant(P<0.05). The tumor size of the central lung squamous cell carcinoma group was significantly larger than that of the peripheral lung squamous cell carcinoma group(P>0.05). The differentiation of patients with central squamous cell carcinoma was significantly worse than that of patients with peripheral squamous cell carcinoma(P<0.05). Patients with central lung squamous cell carcinoma had significantly more cough, hemoptysis, cough, blood stasis, chest pain, chest tightness, wheezing,metastatic symptoms, irritating dry cough, fever, asymptomatic and other clinical symptoms than those with peripheral lung squamous cell carcinoma(P<0.05). Conclusion The main clinical characteristics central lung squamous cell carcinoma and pe

关 键 词：中央型鳞癌 周围型鳞癌 临床特点 CT影像学 

分 类 号：R322.35[医药卫生—人体解剖和组织胚胎学] R734.2[医药卫生—基础医学]