球囊扩张碎栓联合置管溶栓治疗急性下肢深静脉血栓疗效分析  

Efficacy of catheter-directed thrombolysis combined with balloon mashing thrombosis for acute deep vein thrombosis in the lower extremity

作　　者：张章 王磊 阴继凯 王栋 郭松林 ZHANG Zhang;WANG Lei;YIN Ji-kai;WANG Dong;GUO Song-lin(Department of General Surgery, Tangdu Hospital, The Air Force Military Medical University, Xi’an 710038, China)

机构地区：[1]空军军医大学唐都医院普通外科

出　　处：《中国血管外科杂志（电子版）》2019年第2期119-122,共4页Chinese Journal of Vascular Surgery(Electronic Version)

基　　金：陕西省重点研发计划项目(2017ZDXM-SF-038)

摘　　要：目的探讨球囊扩张碎栓联合置管溶栓(CDT)治疗急性下肢深静脉血栓形成(DVT)的疗效。方法回顾性分析2015年3月至2018年4月空军军医大学唐都医院普通外科收治的31例使用球囊扩张碎栓联合CDT治疗的DVT患者临床资料,计算血栓溶解率来评价即时疗效,并检测深静脉通畅率及Villalta评分测定深静脉血栓形成后综合征(PTS)发生率来评价中远期疗效。结果31例患者即时血栓溶解率(91±27)%,成功溶解(血栓溶解率≥50%)28例(90.3%),无严重并发症发生,1、6、12、24个月深静脉再通率分别为93.5%、86.2%、71.4%和55.6%,随访2年后PTS发生率为11.1%。结论急性DVT使用球囊扩张碎栓联合CDT疗效显著,对于病程较长的患者意义更大。Objective To explore the efficacy of catheter-directed thrombolysis (CDT) combined with balloon mashing thrombosis (BMT) for acute deep vein thrombosis (DVT) in the lower extremity. Methods The clinical data of 31 patients with acute DVT of lower extremities treated with CDT and BMT from March 2015 to April 2018 were analyzed retrospectively. Immediate efficacy assessed by thrombus score, deep vein patency and post-thrombotic syndrome (PTS) assessed by Villalta scale were evaluated. Results Of 31 patients, mean thrombus score was (91±27)%, and successful lysis (≥50%) was obtained in 28 patients (90.3)%. No major complications happened. Deep vein patency after 1, 6, 12 and 24 months were 93.5%, 86.2%, 71.4% and 55.6%, respectively. The incidence of PTS was 11.1% at 2 years after surgery. Conclusion CDT combined with BMT for acute DVT is effectively, especially for patients with a longer duration.

关 键 词：下肢深静脉血栓形成 球囊扩张碎栓 置管溶栓 疗效 

分 类 号：R654.4[医药卫生—外科学]