解毒活血汤加减保留灌肠治疗急性盆腔炎(湿瘀互结型)的效果及安全性  

Effect and safety of modified Jiedu Huoxue decoction for retention enema in the treatment of acute pelvic inflammation(damp and blood stasis type)

作　　者：李艳荣 张驰名 LI Yan-rong;ZHANG Chi-ming(Obstetrics and Gynecology Department,Xi'an XD Group Hospital,Xi'an 710077;Internal Medicine Department,Traditional Chinese Medicine Hospital of Chang'an District,Xi'an 710100,China)

机构地区：[1]陕西西安西电集团医院妇产科,陕西西安710077 [2]陕西西安市长安区中医医院内科,陕西西安710100

出　　处：《临床医学研究与实践》2019年第20期106-107,133,共3页Clinical Research and Practice

摘　　要：目的分析解毒活血汤加减保留灌肠治疗急性盆腔炎(湿瘀互结型)的效果及安全性。方法选择我院2016年2月至2017年2月收治的急性盆腔炎(湿瘀互结型)患者120例,随机将其分别为观察组和对照组,各60例。对照组采取静脉滴注头孢呋辛钠及奥硝唑治疗,观察组在此基础上加用解毒活血汤加减保留灌肠治疗。1个疗程后比较两组的治疗效果。结果治疗前,两组患者CRP、TNF-α、IL-6水平比较,差异无统计学意义(P>0.05);治疗后,两组CRP、TNF-α、IL-6水平均显著降低,且观察组明显低于对照组(P<0.05)。观察组体温恢复正常时间、腹痛缓解时间、血WBC计数恢复正常时间及住院时间均显著短于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率显著高于对照组(P<0.05)。结论解毒活血汤加减保留灌肠治疗急性盆腔炎(湿瘀互结型)可明显降低患者炎性细胞因子水平、缩短症状缓解时间,提高疗效,且不良反应少。Objective To analyze the effect and safety of modified Jiedu Huoxue decoction for retention enema in the treatment of acute pelvic inflammation(damp and blood stasis type).Methods A total of 120 patients with acute pelvic inflammatory(damp and blood stasis type)admitted in our hospital from February 2016 to February 2017 were selected and randomly divided into observation group and control group,with 60 cases in each group.The control group was treated with intravenous infusion of cefuroxime sodium and ornidazole.On this basis,the observation group was additionally treated with modified Jiedu Huoxue decoction for retention enema.The treatment effects were compared between the two groups after one course of treatment.Results There were no significant differences in the levels of CRP,TNF-αand IL-6 between the two groups before treatment(P>0.05).After treatment,the levels of CRP,TNF-αand IL-6 of the two groups decreased significantly,and those in the observation group were lower than the control group(P<0.05).The temperature recovery time,abdominal pain relief time,time of blood WBC count returning to normal and hospital stay in the observation group were significantly shorter than those in the control group(P<0.05).The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Modified Jiedu Huoxue decoction for retention enema for acute pelvic inflammatory(damp and blood stasis type)can significantly reduce the levels of inflammatory cytokines,shorten the time of symptom relief and improve the curative effect,with few adverse reactions.

关 键 词：解毒活血汤 保留灌肠 急性盆腔炎 湿瘀互结型 

分 类 号：R286[医药卫生—中药学]