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作 者:俞丁丁 费冬[1] YU Dingding;FEI Dong
机构地区:[1]杭州市余杭区第一人民医院产科
出 处:《新中医》2019年第7期63-65,共3页New Chinese Medicine
摘 要:目的:观察桂枝茯苓丸联合胚宝胶囊治疗慢性盆腔炎的临床治疗效果。方法:将慢性盆腔炎患者68例随机分为对照组和观察组各34例,对照组给予西医常规治疗,观察组在对照组治疗的基础上给予桂枝茯苓丸联合胚宝胶囊,2组均治疗1个月后观察2组患者临床疗效,比较2组患者腹胀、痛经、腰酸、白带异常等症状改善情况,比较2组患者炎症指标包括肿瘤坏死因子-α(TNF-α)、转化因子-β1 (TGF-β1)、C-反应蛋白(CRP)、白细胞介素-6 (IL-6)等指标的浓度变化情况。结果:治疗后,观察组总有效率88.24%,对照组总有效率73.53%,观察组治疗效果明显高于对照组(P <0.05)。治疗前,2组腹胀、痛经、腰酸、白带异常证候积分比较,差异无统计学意义(P> 0.05)。治疗后,2组腹胀、痛经、腰酸、白带异常证候积分均降低,且观察组优于对照组,差异均有统计学意义(P <0.05)。治疗前,2组炎症因子水平比较,差异无统计学意义(P> 0.05)。治疗后,2组炎症因子水平均改善,且观察组明显优于对照组,差异均有统计学意义(P <0.05)。治疗后,对照组不良反应发生率为11.76%,观察组为8.82%,2组比较,差异无统计学意义(P> 0.05)。结论:桂枝茯苓丸联合胚宝胶囊治疗慢性盆腔炎具有较好的临床疗效,可降低患者的中医证候积分和炎症反应,复发率较低,无明显不良反应。Objective:To observe the clinical effect of Guizhi Fuling pills combined with Peibao capsules for chronic pelvic inflammation. Methods:A total of 68 cases of patients with chronic pelvic inflammation were randomly divided into the control group and the observation group, 34 cases in each group. The control group was treated with routine western medicine,and the observation group was additionally treated with Guizhi Fuling pills combined with Peibao capsules based on the treatment of the control group. After one-month treatment, the clinical effect in the two groups was observed;the improvement of symptoms such as abdominal distension,dysmenorrhea,soreness and abnormal leukorrhea in the two groups was compared;the changes of concentration of inflammatory indexes including tumor necrosis factor-α(TNF-α),transforming growth factorβ1(TGF-β1),C-reactive protein(CRP) and interleukin-6(IL-6) in the two groups were compared. Results:After treatment,the total effective rate was 88.24% in the observation group and 73.53% in the control group(P < 0.05). Before treatment,compared the syndrome scores of abdominal distension, dysmenorrhea, soreness and abnormal leukorrhea in the two groups,there was no significance in the difference(P > 0.05). After treatment,the above syndrome scores in the two groups were decreased,and the one in the observation group was better than that in the control group,differences being significant(P < 0.05). Before treatment,there was no significant difference being found in the comparison of the levels of inflammatory factors in the two groups(P > 0.05). After treatment,the levels of inflammatory factors in the two groups were improved,and the decrease in the observation group was significantly larger than that in the control group,differences being significant(P <0.05). After treatment, the incidence of adverse reactions was 11.76% in the control group and 8.82% in the observation group,there being no significance in the difference(P > 0.05). Conclusion:The therapy of Guizhi Fuling pills combin
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