健骨注射液指纹图谱及有效成分的传递  

HPLC fingerprint and transfer of active ingredients in Jiangu injection

作　　者：梁玉婷 王静宇 苏薇薇[1] 幸林广 姚宏亮 林桥辉 彭维[1] LIANG Yuting;WANG Jingyu;SU Weiwei;XING Linguang;YAO Hongliang;LIN Qiaohui;PENG Wei(Guangdong Engineering and Technology Research Center for Quality and Efficacy Re-evaluation of Post-marketed TCM, Sun Yat-sen University, Guangzhou 510275;Guangxi Nanning Baihui Pharmaceutical Group Company Limited, Nanning 530003)

机构地区：[1]中山大学广东省中药上市后质量与药效再评价工程技术研究中心,广东广州510275 [2]广西南宁百会药业集团有限公司,广西南宁530003

出　　处：《中山大学学报（自然科学版）》2019年第4期53-59,共7页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：中山大学科技成果转化类项目(33000-18825004)

摘　　要：采用高效液相色谱法构建了健骨注射液的指纹图谱,研究投料药材、中间体与成品的相关性及有效成分的传递规律。所建立的方法简单、快捷,适用于健骨注射液生产过程质量监控。The study aimed to establish the fingerprint of Jiangu injection (JGI) by the high performance liquid chromatography (HPLC), and analyze the correlation between the raw herbs and effective constituents in JGI. The established method is simple, rapid and reproducible, which is suitable for the production and quality control of JGI.

关 键 词：健骨注射液 战骨药材 中间体 指纹图谱 相关性 

分 类 号：R284.1[医药卫生—中药学]