Biomimetic nanochannel membrane for cascade response of borate and cis-hydroxyl compounds:An IMP logic gate device  

作　　者：Meitao Deng Meng Yang Yaqing Xu Yuqiong Sun Qing Wang Jianbo Liu Jin Huang Xiaohai Yang Kemin Wang 

机构地区：[1]State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, China [2]College of Chemistry Biology and Environment, Yuxi Normal University, Yuxi 653100, China

出　　处：《Chinese Chemical Letters》2019年第7期1397-1400,共4页中国化学快报（英文版）

基　　金：the financial support from the National Natural Science Foundation of China(Nos. 21675047, 21735002 and 21521063);the Key Point Research and Invention Program of Hunan Province(No. 2017DK2011)

摘　　要：Biomimetic nanodevice is an important branch to expand the potential applications of artificial nanochannels. Here, we constructed nanochannels for cascade response of borate and cis-hydroxyl compounds by modifying the nanochannels of track-etched polycarbonate (TEPC) membranes with polyvinyl alcohol (PVA). Firstly, borate bound to PVA and increased the negative charge density on the surface of the nanochannels, which obstructed the transport of 1,5-naphthalene disulfonate (NDS2-). Subsequently, the addition of cis-hydroxyl compounds induced leaving of borate due to the stronger binding affinities between borate and cis-hydroxyl compounds, which reduced the negative charge density on nanochannels and then enhanced the transport of NDS2-. The cascade response of the nanochannels also accord with the properties of IMP (implication) logic gate. In addition, such nanochannels showed good reproducibility and reversibility. Therefore, this cascade response model based on nanochannels has the potential to be used as switches in area of actuators and biosensors, and is also expected to be used to understand the interaction of substances in nanoscale and simulate the physiological functions of boron.Biomimetic nanodevice is an important branch to expand the potential applications of artificial nanochannels.Here,we constructed nanochannels for cascade response of borate and cis-hydroxyl compounds by modifying the nanochannels of track-etched polycarbonate(TEPC)membranes with polyvinyl alcohol(PVA).Firstly,borate bound to PVA and increased the negative charge density on the surface of the nanochannels,which obstructed the transport of 1,5-naphthalene disulfonate(NDS^2).Subsequently,the addition of cis-hydroxyl compounds induced leaving of borate due to the stronger binding affinities between borate and cis-hydroxyl compounds,which reduced the negative charge density on nanochannels and then enhanced the transport of NDS^2.The cascade response of the nanochannels also accord with the properties of IMP(implication)logic gate.In addition,such nanochannels showed good reproducibility and reversibility.Therefore,this cascade response model based on nanochannels has the potential to be used as switches in area of actuato rs and biosensors,and is also expected to be used to understand the interaction of substances in nanoscale and simulate the physiological functions of boron.

关 键 词：BIOMIMETIC NANOCHANNEL CASCADE RESPONSE Logic gate BORATE cis-Hydroxyl compound 

分 类 号：O6[理学—化学]