老年高血压合并腔隙性脑梗死患者发生焦虑抑郁的因素分析  

Analysis of Anxiety and Depression in Elderly Patients with Hypertension Complicated with Lacunar Infarction

作　　者：王静[1] 孙彦豹[1] 刘艳成[1] 金明磊[1] 杨阳[1] 马晓英[1] WANG Jing;SUN Yanbao;LIU Yancheng(Chengde Central Hospital,Hebei Chengde 067000,China)

机构地区：[1]河北省承德市中心医院老年病科

出　　处：《河北医学》2019年第7期1177-1182,共6页Hebei Medicine

基　　金：河北省承德市科学技术研究与发展计划项目,(编号:201701A021)

摘　　要：目的:探讨住院老年高血压合并腔隙性脑梗死患者发生焦虑、抑郁的因素。方法:分别采用汉密尔顿焦虑量表(HAMA-14项),汉密尔顿抑郁量表(HAMD-24项)对承德市中心医院老年病科住院的162例老年高血压合并腔隙性脑梗死患者进行焦虑、抑郁状态评估,并分析焦虑、抑郁的影响因素。采用多因素logistic回归分析相关危险因素。结果:性别、吸烟、颈内动脉斑块在焦虑组与非焦虑组、抑郁组与非抑郁组均无统计学差异(P>0.05),糖尿病、高脂血症、低蛋白血症、衰弱情况、睡眠质量在焦虑组与非焦虑组、抑郁组与非抑郁组均有统计学差异(P<0.05)。焦虑的危险因素为:高脂血症(OR=2.799;95%Cl:1.180~6.638)、低蛋白血症(OR=11.271;95%Cl:1.269~10.084)、衰弱(OR=2.675;95%Cl:1.232~5.809)、睡眠差(OR=3.364;95%Cl:1.559~7.256)。抑郁的危险因素为:高脂血症(OR=4.610;95%Cl:1.505~14.123)、低蛋白血症(OR=5.889;95%Cl:1.863~18.614)、衰弱(OR=4.024;95%Cl:1.674~9.672)、睡眠差(OR=17.405;95%Cl:6.847~44.243)。结论:糖尿病、高脂血症、低蛋白血症、衰弱、睡眠障碍的老年高血压合并腔隙性脑梗死患者更容易发生焦虑、抑郁。Objective:To explore the factor of anxiety and depression in hospitalized elderly hypertension patients combined with lacunar cerebral infarction.Methods:The Hamilton Anxiety Scale(HAMA-14 items)and Hamilton Depression Scale(HAMD-24 items)were used to assess the anxiety and depression status of 162 elderly patients with hypertension and lacunar infarction in Geriatrics Department of Chengde Central Hospital,and to analyze the influencing factors of anxiety and depression.Multivariate logistic regression was used to analyze the related risk factors.Results:The anxiety group and the depression group were compared with the control group,gender,smoking,and carotid plaque were statistically difference(P<0.05);diabetes,hyperlipidemia,hypoalbuminemia,frailty,and sleep quality were no statistical difference(P>0.05).The risk factors of anxiety included living hyperlipidemia(OR=2.799;95%CI:1.180~6.638),hypoproteinemia(OR=11.271;95%CI:1.269~10.084),frailty(OR=2.675;95%CI:1.232~5.809),sleep disorder(OR=3.364;95%CI:1.559~7.256).The risk factors of depression included living hyperlipidemia(OR=4.610;95%CI:1.505~14.123),hypoproteinemia(OR=5.889;95%CI:1.863~18.614),frailty(OR=4.024;95%CI:1.674~9.672),sleep disorder(OR=17.405;95%CI:6.847~44.243).Conclusions:Diabetes mellitus,hyperlipidemia,hypoproteinemia,weakness,sleep disorders in elderly hypertensive patients with lacunar infarction are more likely to develop anxiety and depression.

关 键 词：老年 高血压 腔隙性脑梗死 焦虑 抑郁 

分 类 号：R544.1[医药卫生—心血管疾病] R743.3[医药卫生—内科学]