经鼻高流量吸氧对ICU呼吸衰竭患者血气指标及APACHEⅡ评分影响研究  

Effects on APACHE Ⅱ and blood gas index in with respiratory failure in ICU by using high-flow transnasal oxygen inhalation

作　　者：王诚 徐非凡[1] 曹昊[1] 吕学斌[1] WANG Cheng;XU Fei-fan;CAO Hao;LYU Xue-bin(Department of Critical Care Medicine,Chizhou People′s Hospital,Anhui Province,Chizhou 247000,China)

机构地区：[1]安徽省池州市人民医院重症医学科

出　　处：《创伤与急危重病医学》2019年第4期239-241,共3页Trauma and Critical Care Medicine

摘　　要：目的探究经鼻高流量吸氧对ICU呼吸衰竭患者血气指标及急性生理与慢性健康评分量表(APACHEⅡ)评分的影响。方法选择60例ICU内行机械通气并拔管的呼吸衰竭患者为研究对象,分为低氧组、观察组,每组30例。低氧组采用面罩低流量氧疗治疗,观察组采用经鼻高流量吸氧治疗。比较两组患者的呼吸相关指标、再插管率、ICU停留时间、住院时间以及APACHEⅡ评分。结果观察组的再插管率、ICU停留时间、住院时间均低于低氧组,差异有统计学意义(P<0.05)。治疗后,两组患者的APACHEⅡ、二氧化碳分压评分均明显降低,观察组患者显著低于低氧组,差异有统计学意义(P<0.05)。治疗后,两组患者的血氧饱和度、氧分压升高,且观察组高于低氧组,差异有统计学意义(P<0.05)。结论经鼻高流量吸氧可有效改善ICU呼吸衰竭患者血气指标,降低再插管率,缓解病情并帮助患者康复。Objective To investigate the nasal high flow oxygen therapy in patients with respiratory failure in the ICU blood gas index and acute physiology and chronic health evaluation scale(APACHE Ⅱ)score. Methods A retrospective study was performed on 60 cases of patients with respiratory failure in ICU who were performed nasal high flow oxygen therapy.The patients were divided into the hypoxic group and the observation group,with 30 cases in each group.The hypoxic group of patients were treated with mask low flow oxygen therapy,while the observation group of patients were treated with nasal high flow oxygen therapy.Two groups of patients with respiratory related indicators,reintubation rates,ICU stay time,length of hospital stay and APACHE Ⅱ score were compared. Results The rate of re-intubation,length of stay in ICU and length of stay in hospital in the observation group were lower than those in the hypoxic group,with statistically significant differences( P <0.05).After treatment,two groups of patients with APACHE Ⅱ,PaCO 2 scores were significantly lower,observation group of patients were significantly lower than those of hypoxic groups( P <0.05).After treatment,SpO 2 and PaO 2 levels in the two groups increased,and the levels of observation group were higher than those of the hypoxia group( P <0.05). Conclusion High-flow transnasal oxygen inhalation can effectively improve the blood gas index of ICU respiratory failure patients,reduce the rate of re-intubation,alleviate the disease and help patients recover.

关 键 词：经鼻高流量吸氧 呼吸衰竭 ICU 急性生理与慢性健康评分量表 

分 类 号：R563.8[医药卫生—呼吸系统]