ICU转出患者病情变化的原因分析  

Analyses on causes of disease condition changes for patients discharged from intensive care unit

作　　者：徐采云[1] 刘素霞[1] 徐慧玲[1] 刘克喜[1] 宋甲富 Xu Caiyun;Liu Suxia;Xu Huiling;Liu Kexi;Song Jiaju(Department of Intensive Care Medicine,the First People's Hospital of Lianyungang City,Lianyungang 222061,Jiangsu,China;Department of Respiratory,The First Peoples Hospital of Lianyungang City,Lianyungang 222061,Jiangsu,China)

机构地区：[1]连云港市第一人民医院重症医学科,江苏连云港222061 [2]连云港市第一人民医院呼吸科,江苏连云港222061

出　　处：《中国中西医结合急救杂志》2019年第3期261-264,共4页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：目的探讨综合重症医学科(ICU)转出患者在普通病房发生病情变化的原因.方法回顾性分析2013年1月至2018年12月连云港市第一人民医院综合ICU病情改善转入普通病房患者的临床资料.收集患者的一般情况,如性别、年龄、基础疾病、吸烟情况、24h内急性生理学与慢性健康状况评分Ⅱ(APACHEⅡ)和格拉斯哥昏迷评分(GCS)、ICU住院时间、ICU内平均氧合指数和平均呼吸频率、转出当日氧合指数和呼吸频率、转出前GCS评分、是否为有创通气、有创通气时间、是否发生脓毒症、社区或院内获得性肺炎等情况及转出后病情变化分类.根据转科患者在普通病房是否发生病情变化分为病情变化组和病情稳定组,再根据是否发生呼吸系统并发症分为有呼吸系统并发症组和无呼吸系统并发症组;采用多因素Logistic回归分析导致病情变化的危险因素.结果2013年1月至2018年12月本院综合ICU共收治2451例患者,其中转至普通病房1293例;发生病情变化628例.①转出ICU患者发生病情变化的原因以呼吸系统并发症最为常见(345例,占54.9%),其次为心血管系统并发症(118例,占18.8%)和手术相关并发症(96例,占15.3%).②病情变化组合并基础疾病和大量吸烟的比例显著高于病情稳定组〔24.4%(153/628)比7.8%(52/665),40.3%(253/628)比24.2%(161/665),均P<0.05〕.与病情稳定组比较,病情变化组ICU住院期间平均氧合指数低〔mmHg(1mmHg=0.133kPa):238.91±71.14比291.74±63.64〕,转出当日氧合指数低(mmHg:261.23±58.11比301.00±58.25),有创通气比例高〔64.2%(403/628)比47.4%(315/665)〕,有创通气时间长〔d:5(2~9)比3(2~7)〕,差异均有统计学意义(均P<0.05).③与无呼吸系统并发症组比较,有呼吸系统并发症组ICU住院期间平均氧合指数低(mmHg:216.43±67.17比264.85±78.46)、转出当日氧合指数低(mmHg:250.72±74.93比274.87±81.79)、有创通气比例高〔77.4%(267/345)比48.1%(136/283)〕,差异均有Objective To investigate the causes of disease condition changes after the patients' transfer from intensive care unit (ICU) into the general wards. Methods From January 2013 to December 2018, the patients with improvement of disease condition in comprehensive ICU were transferred into the general wards of the First People's Hospital of Lianyungang and their clinical data were retrospectively analyzed. The general information of patients was collected, such as gender, age, underlying diseases, heavy smoking, acute physiology and chronic health evaluationⅡ(APACHEⅡ) and Glasgow coma score (GCS) in 24 hours, length of stay in ICU, average levels of oxygenation index and respiratory rates during the stay in ICU and on the day transfer from ICU, GCS score on the day of transfer from ICU, presence or absence of invasive ventilation,the time of invasive ventilation, sepsis or its absence, the situation of community or hospital acquired pneumonia, etc, and the classification of the disease changes after transfer. The patients were divided into a disease situation change group (change group) and a disease situation stable group (stable group) according to whether there was any change in the disease situation in the general ward or not, the patients were divided into respiratory complications group and non-respiratory complications group. The risk factors that may influence the change of the disease condition were analyzed by multiple-factor Logistic regression. Results From January 2013 to December 2018, there were 2 451 patients treated in comprehensive ICU, of that 1 293 were transferred into the general wards for further treatment. Among the patients transferred to the general ward, 628 cases' conditions were changed.① The respiratory complications were the most common changes (345 cases, 54.9%) in patients after the transfer from ICU, followed by cardiovascular complications (118 cases, 18.8%) and surgery-related complications (96 cases, 15.3%).② The proportions of underlying diseases and heavy smoking in the

关 键 词：基础病 大量吸烟 平均氧合指数 转出重症医学科 病情变化 

分 类 号：R193[医药卫生—卫生事业管理]