心脏磁共振成像评估心肌淀粉样变性的研究进展  

The research progress of cardiac magnetic resonance in diagnosis of myocardial amyloidosis

作　　者：崔倩[1] 于静[1] 沈文[1] Cui Qian;Yu Jing;Shen Wen(Tianjin First Center Hospital,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院,300192

出　　处：《中国中西医结合急救杂志》2019年第3期382-384,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

摘　　要：淀粉样变性累及心脏时预后较差,早期诊断并治疗对患者预后有重要影响.心脏磁共振成像(CMRI)可对心脏进行"一站式"检查,完成对心脏形态及功能的评价."一站式"的CMRI可呈现心肌肥厚、心脏舒张功能障碍、心内膜下强化(斑片状、弥漫性或透壁性)、升高的T1值、过快的对比剂血池廓清速率及心包和胸腔积液,可提高诊断效力.CMRI与心肌组织相关性好,对心肌淀粉样变性的早期诊断、明确心脏受累情况作用显著,可重复检查、纵向随访患者、监测药物疗效、指导治疗及判断预后等,具有很高的临床应用价值.Cardiac involvement in amyloidosis has a relatively poor prognosis, and early diagnosis and treatment is very important to the prognosis of such involved patients."One stop type" cardiac examination can be carried out by the cardiac magnetic resonance imaging (CMRI) and the evaluation of cardiac morphology and function can be complete."One stop type" CMRI may show the thickness of myocardium in left ventricle, cardiac diastolic dysfunction, sub-endocardial enhancement (patch, diffuse and transmural types), rising of T1 value, too fast clarifying rate of contrast agent in blood pool, pericardial and/or pleural cavity effusion, that may help to elevate the efficiency of diagnosis. The CMRI presents myocardial tissue characteristics quite well, that may help for early diagnosis of myocardial amyloidosis, and clearly demonstrate the situation of heart involvement;to follow-up patients with repeat CMRI examinations can monitor drug therapeutic effect, direct and regulate treatment, judge prognosis, etc. so that CMRI possesses very high clinical application value.

关 键 词：心肌淀粉样变性 心脏磁共振成像 

分 类 号：R542.2[医药卫生—心血管疾病]