皮耐克在创面治疗中应用的研究进展  

Advances in the application progress of Pelnac in wound therapy

作　　者：涂振阳 蓝常贡[2] 罗群强[3] 周传晓[3] 农峰[4] 周洋 唐盛斐 TU Zhenyang;LAN Changgong;LUO Qunqiang;ZHOU Chuanxiao;NONG Feng;ZHOU Yang;TANG Shengfei(Grade 2017,Graduate School of Youjiang Medical College for Nationalities ,Baise 533000,China;Department of Spinal Orthopedic Surgery ,Affiliated Hospital of Youjiang Medical College for Nationalities i Baise 533000,China;Hand and Foot Surgery ,Affiliated Hospital of Youjiang Medical College for Nationalities ,Baise 533000,China;Department of Cardiothoracic Surgery ,Affiliated Hospital of Youjiang Medical College for Nationalities ,Baise 533000? China;Department of Ultrasound Diagnosis ,Guangzhou Red Cross Hospital,Guangzhou 510235 ,China)

机构地区：[1]右江民族医学院研究生学院2017级,广西壮族自治区百色533000 [2]右江民族医学院附属医院脊柱骨病外科,广西壮族自治区百色533000 [3]右江民族医学院附属医院手足外科,广西壮族自治区百色533000 [4]右江民族医学院附属医院心胸外科,广西壮族自治区百色533000 [5]广州市红十字会医院超声诊断科,510235

出　　处：《中华实用诊断与治疗杂志》2019年第7期720-723,共4页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金(81660369);广西自然科学基金(2016GXNSFAA380173)

摘　　要：创面是指机体皮肤和软组织连续性中断而形成的缺损,传统治疗方法包括更换敷料、清创缝合、植皮和皮瓣转移术等,但具有治疗时间长、愈合后外观臃肿等缺点。因此,亟需寻找一种愈合快、瘢痕少的治疗方法。皮耐克是以无末端猪胶原蛋白为支架、硅胶膜为表层的人工真皮,具有良好生物相容性,利于创面愈合,在联合植皮和皮瓣转移术中可提高皮片和皮瓣成活率,广泛用于糖尿病足、骨骼和肌腱外露、烧伤等创面的治疗。本文就皮耐克在创面治疗中应用的研究进展作一综述。Wound is a defect caused by the interruption of skin and soft tissue continuity. The traditional treatment methods include dressing change, debridement suture, skin graft and flap transfer, but the treatment time is long, and appearance is bloated after healing. Therefore, it is urgent to find a treatment method with quick healing and less scar. Pelnac is an artificial dermis with terminal-free pig collagen as the scaffold and silicon membrane as the surface. Pelnac has good biocompatibility and is good for wound healing, and it improve the survival rate of skin and flaps in combined skin grafting and flap transplantation, therefore it has been widely used in the treatment of diabetic foot ulcers, bone and tendon exposure, as well as burn wound. This paper reviews the research progress of Pelnac in wound therapy.

关 键 词：创面愈合 皮耐克 糖尿病足 骨外露 肌腱外露 烧伤 

分 类 号：R641[医药卫生—外科学]