老年溃疡性结肠炎临床特点分析  

Clinical characteristics of ulcerative colitis in elderly cases

作　　者：胡义亭[1] 张建[1] 刘洪娜[1] 苏少慧[1] 白云[1] 赵红伟[1] HU Yi-ting;ZHANG Jian;LIU Hong-na;SU Shao-hui;BAI Yun;ZHAO Hong-wei(Department of Gastroenterology,Hebei Provincial People's Hospital,050051 Shijiazhang,Hebei,China)

机构地区：[1]河北省人民医院消化科

出　　处：《临床消化病杂志》2019年第3期163-166,共4页Chinese Journal of Clinical Gastroenterology

基　　金：河北省医学科学研究重点课题计划(No.20160067)

摘　　要：[目的]探讨老年溃疡性结肠炎患者的临床特征。[方法]将本院2010-01-2017-10期间收治的溃疡性结肠炎患者142例,根据年龄分为老年组和非老年组。老年组46例,年龄(65.8±5.3)岁;非老年组96例,年龄(46.5±3.2)岁。比较2组患者的临床资料,包括疾病分型、范围、病情严重程度、临床表现及并发症。统计并比较2组患者入院当天的实验室各项指标检测情况,包括:红细胞沉降率(ESR)、血小板(PLT)、白细胞计数(WBC)、血红蛋白(HGB)、凝血酶原时间(PT)、血清白蛋白(ALB)、C反应蛋白(CRP)。统计各组临床药物治疗情况及临床疗效。[结果]老年组患者病变范围较局限,病情较轻。老年组PLT计数超过正常上限患者比率明显高于非老年组(P<0.01)。2组临床症状、不良反应及其他实验室检查指标比较差异无统计学意义(P>0.05)。老年组使用糖皮质激素的患者比率明显低于非老年组,2组比较差异有统计学意义(P<0.01),但2组临床缓解率比较差异无统计学意义(P>0.05)。[结论]老年溃疡性结肠炎患者在疾病累及范围、病变严重程度、实验室检查等方面均不同于非老年者,体现了老年溃疡性结肠炎患者自身的疾病特点。[Objective]To compare the clinical characteristics of ulcerative colitis between elderly and non-elderly patients.[Methods]There were 142 cases of ulcerative colitis were admitted in the hospital from January 2010 to October 2017,which were divided into elderly group(n=46)and non-elderly group(n=96).The average age of the two groups were(65.8±5.3)and(46.5±3.2)years old respectively.The clinical data of the two groups were collected and compared,including the lesion type,colon image,severity,clinical manifestation and complications.The laboratory indexes of the two groups were measured and compared,including ESR,PLT,WBC,HGB,PT,ALB,CRP.The clinical medicine treatment and clinical efficacy of each group were statistically analyzed.[Results]Patients in the elderly group had a limited range of lesions,and their condition was milder.The ratio of PLT to the normal top range was significantly higher than that of the non-elderly group(P<0.01).There was no significant difference between the two groups of clinical symptoms,adverse reactions and other laboratory examination indicators(P>0.05).The elderly-group had significantly lower rates of glucocorticoid than non-elderly patients and the difference was statistically significant(P<0.01).However,there was no significant difference of clinical improvement ratebe-tween the two groups(P<0.05).[Conclusion]The elderly patients with ulcerative colitis are different from other groups in terms of the range of disease,severity of disease and laboratory examination,which reflect certain characteristics and differences.

关 键 词：结肠炎 溃疡性 老年 临床特点 

分 类 号：R574.62[医药卫生—消化系统]