不同孕周胸腺-胸廓比评价胎儿胸腺发育的价值分析  

Value of thymus-thoracic ratio in different gestational weeks for evaluation of fetal thymus development

作　　者：陈萍 佘玲娜[1] 陈荔艳 姚思平 CHEN Ping;SHE Ling-na;CHEN Li-yan

机构地区：[1]广东省梅州市人民医院超声科

出　　处：《中国产前诊断杂志（电子版）》2019年第2期54-56,共3页Chinese Journal of Prenatal Diagnosis(Electronic Version)

摘　　要：目的分析不同孕周胸腺-胸廓比值与胎儿胸腺发育的相关性。方法收集2018年1月至2019年2月来本院进行产前筛查的210名健康孕妇(18~45岁),胎龄18~39周,在三血管-气管(3VT)切面上观察正常胎儿的胸腺特征,并测量从胸骨后缘到主动脉前缘的距离(T1值)、从胸骨后缘到椎体前缘的距离(T2值),两者的比值为T-T值(即胎儿胸腺-胸廓比)。绘制T-T值的散点图,并进行Spearman回归分析。结果3VT切面显示胎儿胸腺位于前上纵隔,呈不规则“四边形”低回声结构。210例胎儿T-T平均值为0.45±0.05。T-T值与孕龄无相关性(r=0.08,P=0.29)。结论产前超声检查可通过测量T-T值评估胸腺大小,并为胎儿胸腺缺乏或发育不良提供诊断依据。Objective To analyze the correlation between thymus-thoracic ratio and fetal thymus development in different gestational weeks. Methods A total of 210 healthy pregnant women (18~45y) who underwent antenatal screening from January 2018 to February 2019 were enrolled. The gestational age ranged from 18 to 39 weeks. Thymus characteristics of normal fetal was performed on the trivascular-tracheal (3VT) section, and measure the distance from the posterior border of the sternum to the leading edge of the aorta (T1 value), the distance from the posterior border of the sternum to the anterior edge of the vertebral body (T2 value), the ratio of the two is TT (fetal thymus-thoracic ratio). A scatter plot of the T-T values was plotted and Spearman regression analysis was performed. Results The 3VT section showed that the fetal thymus was located in the anterior superior mediastinum, with an irregular “quadrilateral” hypoechoic structure. The average fetal T-T value was 0.45±0.05. There was no correlation between T-T value and gestational age ( r =0.08, P =0.29). Conclusions Prenatal ultrasound can assess the size of the thymus by measuring T-T values and provide a basis for diagnosis of fetal thymus deficiency or dysplasia.

关 键 词：超声检查 产前 胎儿 胸腺 T-T值 

分 类 号：R445.1[医药卫生—影像医学与核医学]