紫苏叶油浸剂对早期断奶仔猪应激综合征的保护作用  

Protective Effect of Perilla Leaf Oil Extract on Stress Syndrome of Early Weaned Piglets

作　　者：景俊年 苏金辉 夏冰 王九峰[1] JING Jun-nian;SU Jin-hui;XIA Bing;WANG Jiu-feng(College of Veterinary Medicine , China Agricultural University , Beijing 100193 , China)

机构地区：[1]中国农业大学动物医学院

出　　处：《中国兽医杂志》2019年第4期3-6,I0001,共5页Chinese Journal of Veterinary Medicine

基　　金：国家重点研发计划资助(2017YFD0502200)

摘　　要：为了探究紫苏叶油浸剂对大豆抗原引起断奶仔猪应激综合征的影响,通过建立断奶仔猪模型,研究豆粕中的大豆抗原对仔猪的临床及病理变化等以及紫苏叶油浸剂在该过程中所发挥的作用。将18头21日龄断奶仔猪随机均分为对照组(CN)、高豆粕组(HS)和高豆粕加紫苏叶油浸剂保护组(PL)三组。HS组腹泻率显著高于CN组(P<0.05),而PL组与CN组没有差异,说明添加紫苏叶降低了仔猪豆粕抗原引起的腹泻率。在第3、5、7天,HS组髓过氧化物酶(MPO)水平显著高于CN组和PL组(P<0.05),第3、5天,HS组α1抗胰蛋白酶(α1AT)高于CN组和PL组(P<0.05)。HS组存在一定的炎症反应,而添加紫苏叶油浸剂表现出改善作用。在空肠,添加紫苏叶可以显著减缓黏膜下层水肿程度、改善黏膜充血状况。在回肠,PL组肠炎评分与HS组存在显著性差异(P<0.05),空肠差异不显著,表明添加紫苏叶起到的保护性作用主要发生在回肠。In order to investigate the effect of perilla leaf oil extract on the stress syndrome of weaned piglets caused by soybean antigen, we established a weaned pig model to study the clinical and pathological changes of early weaned piglets and the protective role of perilla leaf oil extract. Eighteen 21-day-old weaned piglets were randomly divided into control group (CN), high soybean meal group(HS) and high soybean meal plus perilla leaf oil extract adsorptive powder group (PL). The diarrhea rate in the HS group was significantly higher than that in the CN group (P <0. 05), but there was no difference between the PL group and the CN group, indicating that the addition of perilla leaves could alleviate the diarrhea caused by soybean antigen. On the 3rd, 5th and 7th day, the level of myeloperoxidase (MPO) in HS group was significantly higher than that in CN group and PL group. On the 3rd and 5th day,α1 antitrypsin (α1AT) in HS group was higher than than in CN group and PL group (P <0. 05). There was a certain inflammatory reaction in the HS group, and the addition of the perilla leaf oil extract showed an improvement. In the jejunum, the addition of pe- rilla leaves alleviated submucosal edema and mucosal congestion. In the ileum, there was a significant difference between the PL group and the HS group(P <0. 05), and the jejunal difference was not significant, indicating that the protective effect of the addition of perilla leaves mainly occurres in the ileum.

关 键 词：紫苏叶 大豆抗原 应激综合征 断奶仔猪 

分 类 号：S852.61[农业科学—基础兽医学]