机构地区:[1]佛山市中医院三水医院
出 处:《中国现代药物应用》2019年第14期85-87,共3页Chinese Journal of Modern Drug Application
摘 要:目的探究跌打七厘片联合双氯芬酸二乙胺乳胶剂治疗急性软组织损伤性疼痛的临床效果。方法200例急性软组织损伤性疼痛患者,随机分为对照组与观察组,各100例。对照组应用双氯芬酸二乙胺乳胶剂治疗,观察组应用跌打七厘片联合双氯芬酸二乙胺乳胶剂治疗。对比两组患者治疗效果、治疗前后视觉模拟评分法(VAS)评分以及不良反应发生情况。结果治疗后,观察组显效72例、有效26例、无效2例,治疗总有效率为98.00%;对照组显效43例、有效32例、无效25例,治疗总有效率为75.00%;观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗前,观察组VAS评分为(7.23±1.45)分,对照组VAS评分为(7.12±1.36)分,比较差异无统计学意义(P>0.05)。治疗后,观察组VAS评分为(1.46±0.05)分,对照组VAS评分为(5.57±1.03)分;两组VAS评分均低于治疗前,且观察组VAS评分明显低于对照组,差异有统计学意义(P<0.05)。观察组发生皮肤瘙痒1例、皮疹2例、皮肤发红0例,不良反应发生率为3.00%;对照组发生皮肤瘙痒2例、皮疹1例、皮肤发红1例,不良反应发生率为4.00%。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论跌打七厘片联合双氯芬酸二乙胺乳胶剂能改善急性软组织损伤性疼痛,临床效果显著,值得在临床中推广应用。Objective To investigate the clinical effect of Dieda Qili tablet combined with diclofenac diethylamine emulgel in the treatment of acute soft tissue injury pain. Methods A total of 200 patients with acute soft tissue injury pain were randomly divided into control group and observation group, with 100 cases in each group. The control group was treated with diclofenac diethylamine emulgel, and the observation group was treated with Dieda Qili tablet combined with diclofenac diethylamine emulgel. Comparison were made on treatment effect, visual analogue scale(VAS) score and occurrence of adverse reactions between the two groups. Results After treatment, the observation group had 72 excellent cases, 26 effective cases and 2 ineffective cases, with total treatment effective rate as 98.00%. The control group had 43 excellent cases, 32 effective cases and 25 ineffective cases, with total treatment effective rate as 75.00%. The observation group had obviously higher total treatment effective rate than the control group, and the difference was statistically significant(P<0.05). Before treatment, the observation group had VAS score as(7.23±1.45) points, and the control group had VAS score as(7.12± 1.36) points. The difference was not statistically significant(P>0.05). After treatment, the observation group had VAS score as(1.46±0.05) points, and the control group had VAS score as(5.57±1.03) points. Both groups had lower VAS score than those before treatment, and the observation group had obviously lower VAS score than the control group. Their difference was statistically significant(P<0.05). The observation group had 1 case of pruritus, 2 cases of rash and 0 case of skin redness, with incidence of adverse reactions as 3.00%. The control group had 2 cases of pruritus, 1 case of rash and 1 case of skin redness, with incidence of adverse reactions as 4.00%. There was no statistically significant difference in incidence of adverse reactions(P>0.05). Conclusion Dieda Qili tablet combined with diclofenac diethylamine emulge
关 键 词:跌打七厘片 双氯芬酸二乙胺乳胶剂 急性软组织损伤性疼痛
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