丹菊葛芩汤联合苯那普利对老年高血压患者血流动力学及心血管体液因子的影响  

Influence of Danju Geqin Decoction combined with Benazepril on hemodynamics and cardiovascular humoral factors of elderly patients with hypertension

作　　者：赵影 袁林 ZHAO Ying;YUAN Lin(Department of Outpatient,Integrated Traditional Chinese and Western Medicine Hospital of Guangzhou City,Guangdong Province,Guangzhou 510800,China)

机构地区：[1]广州市中西医结合医院门诊部

出　　处：《中国当代医药》2019年第20期144-147,共4页China Modern Medicine

摘　　要：目的探讨丹菊葛芩汤联合苯那普利对老年高血压患者血流动力学及心血管体液因子的影响。方法随机选取2017年11月~2018年11月我院门诊就诊的94例老年高血压患者,根据随机数字表法分为观察组与对照组,各47例。对照组单独采用苯那普利治疗,观察组给予丹菊葛芩汤联合苯那普利治疗。比较两组治疗前后的血流动力学指标、心血管体液因子变化及治疗效果。结果两组治疗前的心率、收缩压、舒张压水平比较,差异无统计意义(P>0.05)。两组治疗后的心率、收缩压、舒张压水平均显著低于治疗前,差异有统计学意义(P<0.05)。观察组治疗后的心率、收缩压、舒张压水平显著低于对照组,差异有统计意义(P<0.05)。两组治疗前的内皮素、心房肽、血管紧张素水平比较,差异无统计意义(P>0.05)。两组治疗后的心房肽、血管紧张素水平显著低于治疗前,内皮素水平显著高于治疗前,差异有统计学意义(P<0.05)。观察组治疗后的心房肽、血管紧张素水平显著低于对照组,内皮素水平显著高于对照组,差异有统计学意义(P<0.05)。观察组的治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。结论丹菊葛芩汤联合苯那普利可降低高血压患者的舒张压和收缩压,促进患者心血管体液因子的正常,提高疾病的治疗效果,值得临床推广应用。Objective To explore the influence of Danju Geqin Decoction combined with Benazepril on hemodynamics and cardiovascular humoral factors in elderly patients with hypertension.Methods A total of 94 elderly patients with hypertension admitted to our hospital from November 2017 to November 2018 were randomly selected.According to the method of random number table,all patients were divided into the observation group and the control group,with 47 cases in each group.The patients in the control group were treated with Benazepril alone,while the patients in the observation group were treated with Danju Geqin Decoction combined with Benazepril.The hemodynamics and vascular humoral factors before and after treatment and the therapeutic effect of the two groups were compared.Results There was no statistical difference in the heart rate,systolic blood pressure and diastolic blood pressure between the two groups before treatment (P>0.05).The level of heart rate,systolic blood pressure and diastolic blood pressure of the two groups after treatment were significantly lower than those before treatment,and the difference was statistically significant (P<0.05).After treatment,the level of heart rate,systolic blood pressure and diastolic blood pressure in the observation group were significantly lower than those in the control group,with statistical significance (P<0.05).There was no statistical difference in the levels of endothelin,atrial peptide and angiotensin between the two groups before treatment (P>0.05).After treatment,the levels of atrial peptide and angiotensin in the two groups were significantly lower than those before treatment,and the levels of endothelin in the two groups were significantly higher than those before treatment,the difference was statistically significant (P<0.05).After treatment,the levels of atrial peptide and angiotensin in the observation group were significantly lower than those in the control group,and the levels of endothelin in the observation group were significantly higher than those in the c

关 键 词：丹菊葛芩汤 苯那普利 高血压 血流动力学 心血管体液因子 

分 类 号：R544.1[医药卫生—心血管疾病]