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作 者:张惠玲[1] 许会军[1] 吴小良[1] 李静[1] 陈晓芳[1] 赵鹏[1] 刘朝兴[1] 李鹏 ZHANG Huiling;XU Huijun;WU Xiaoliang;LI Jing;CHEN Xiaofang;ZHAO peng;LIU Chaoxing;LI Peng(Department of Radiotherapy,First Hospital of Shijiazhuang,Shijiazhuang Hebei 050011,China)
机构地区:[1]石家庄市第一医院放疗科
出 处:《中国医疗设备》2019年第8期81-84,共4页China Medical Devices
基 金:石家庄市科学技术研究与发展计划项目(171462203)
摘 要:目的分析加速器多叶准直器(Multi-Leaf Collimator,MLC)叶片位置校准对胸部调强计划(Intensity Modulated Radiation Therapy,IMRT)验证结果的影响。方法应用Delta4三维剂量验证系统,分别在MLC校准前、后测量胸部肿瘤患者IMRT计划,分析其Dose deviation(DD)、DTA、Gamma通过率的差异。结果在DD、DTA、Gamma通过率三种评价指标中,MLC校准后9例胸部患者IMRT计划的通过率均有所提高。校准MLC前、后评价指标2%DD、2 mm DTA、2%/2 mm Gamma的平均通过率分别增加了19.29%、22.86%、19.53%,而当评价指标为4%DD、4 mm DTA、4%/4 mm Gamma时的平均通过率增加有所降低分别为17.27%、3.48%、2.86%,即评价指标4%DD、4 mm DTA、4%/4 mm Gamma通过率对MLC的位置误差更不敏感。结论调强放疗MLC的叶片位置精度直接影响计划验证的通过率,IMRT计划验证通过率下降时应考虑检测MLC的叶片位置精度。Objective To analyze the influence of MLC leaf position calibration on the chest IMRT verification.Methods The 3D Dosimetric verification system of Delta4 was used to measure the IMRT plan of chest tumor patients before and after MLC calibration,and to analyze the differences of Dose deviation(DD),Distance to Agreement(DTA)and Gamma pass rate.Results When the three evaluation indexes of DD,DTA and gamma pass rate were applied,the pass rates of the IMRT plan of 9 chest patients after MLC calibration were all improved.The average pass rate of 2%DD,2 mm DTA,2%/2 mm Gamma after MLC calibration increased by 19.29%,22.86%,19.53%,respectively.When the evaluation indexes were 4%DD,4 mm DTA,and 4%/4 mm Gamma,the increase in the average pass rate was moderate,with 17.27%,3.48%,and 2.86%,respectively.Thus,the evaluation indicators 4%DD,4 mm DTA,and 4%/4 mm Gamma were less sensitive to the position errors of MLC.Conclusion The pass rate of dose verification was directly affected by the precision of MLC leaf position in IMRT,if it decreased,the position precision of MLC leaf should be considered.
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