双丹酰基组氨酸作为Fe3+荧光探针的研究  

A Study of Fluorescent Probe for Fe3+ Based on Didansyl-Histidine

作　　者：邓乐芳[1,2] 苏晓萍 李敏 古雯蕾[1] 马立军 DENG Lefang;SU Xiaoping;LI Min;GU Wenlei;MA Lijun(School of Chemistry and Environment,South China Normal University,Guangzhou 510006,China;Zengcheng Senior High School,Guangzhou 511316,China)

机构地区：[1]华南师范大学化学与环境学院,广州510006 [2]广州市增城高级中学,广州511316

出　　处：《华南师范大学学报（自然科学版）》2019年第4期26-31,共6页Journal of South China Normal University(Natural Science Edition)

基　　金：广东省自然科学基金项目(2015A030313392);广州市科技计划资助项目(2018J2200342)

摘　　要：以丹磺酰基为荧光基团、以组氨酸为识别基团,设计并合成了一种识别Fe^3+的双丹酰基组氨酸(DHD)荧光探针.通过核磁共振波谱、质谱、紫外-可见吸收光谱、荧光光谱等对产物进行了表征和识别性能的研究.结果表明:探针分子能够在水溶液中以物质的量1∶1的结合比荧光识别Fe^3+,表现出高灵敏度和高选择性,且具有很强的抗离子干扰能力和荧光恢复能力.The fluorescent probe for Fe^3+based on Didansyl-Histidine(DHD)was designed and synthesized using dansyl as fluorophore and histidine as receptors.The characterization and coordination mechanisms were researched with NMR,mass spectra,UV-Vis absorption spectroscopy,fluorescent spectroscopy and other methods.The experi-ments results indicated that DHD and Fe^3+formed a multidentate complex with a molar ratio of 1∶1.This probe showed high sensitivity and specific selectivity for Fe^3+and exhibited a strong antijamming ability over other examined metal ions and good reversibility in the responses of DHD to Fe^3+.

关 键 词：荧光探针 FE3+ 丹磺酰基团 组氨酸 

分 类 号：TN27[电子电信—物理电子学]