从肺肠合治法论治溃疡性结肠炎  

“Lung and Intestine Combined Therapy” in the Treatment of Ulcerative Colitis

作　　者：党琳[1] 秦松林[1] DANG Lin;QIN Songlin(Basic Medical School, Shaanxi University of Chinese Medicine,Xianyang 712046,Shaanxi Province,China)

机构地区：[1]陕西中医药大学基础医学院

出　　处：《吉林中医药》2019年第7期841-844,共4页Jilin Journal of Chinese Medicine

基　　金：国家自然科学基金项目(81603420);陕西省教育厅2018重点科学研究计划项目(18JS029);陕西省教育厅专项科研计划项目(16JK1197)

摘　　要：肺肠合治法来源于肺与大肠相表里理论。肺和大肠在经脉上相互络属,在功能上相互协调、病理上相互影响、治疗上相互为用。肺肠合治法契合了溃疡性结肠炎治疗的中西医理论基础,且血管活性肠肽、肠道菌群以及信号转导通路等从分子层面也论证了其相关性。治疗当从肺肠合治出发,采用清热利湿、宣肺通腑,温中涩肠、补肺疏肝,调肺畅中、行瘀解毒等方法,畅肺肠之气,补肺肠之虚。Ulcerative colitis is a chronic nonspecific inflammatory intestine disease. Currently, the use of modern medical therapy shows no stable curative effect, and problems such as hepatorenal toxicity and drug dependence could occur at the same time. Comparatively, Chinese medical therapy could effectively control the symptoms of patients without obvious side effects. The author expounds the theoretical basis of Chinese and Western medicine for the treatment of ulcerative colitis from a new perspective of "lung and intestine combined therapy" on ground of three modern molecular levels including vasoactive intestinal peptide, intestinal flora and signal transduction pathway. The therapeutic methods include clearing away heat and dampness, dispersing lung and dredging Fu organs,warming spleen and stomach for astringing intestine, invigorating lung and soothing liver, regulating lung and smooth,removing blood stasis and detoxifying. It provides a new idea for the treatment of ulcerative colitis.

关 键 词：肺肠合治 溃疡性结肠炎 中医药治疗 宣肺通腑 温中补肺 

分 类 号：R242[医药卫生—中医临床基础]