抗阻运动对降低2型糖尿病患者心血管事件发生风险的效果研究  

Effects of resistance training on cardiovascular disease risk in type 2 diabetes patients

作　　者：杨丽红 周欢欢[2] 袁晓丹[1] 李佳凝 楼青青[1] YANG Lihong;ZHOU Huanhuan;YUAN Xiaodan;LOU Qingqing(Health Education Section,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210028,China)

机构地区：[1]南京中医药大学附属中西医结合医院健康教育科,210028 [2]常州市第一人民医院心胸外科

出　　处：《中国糖尿病杂志》2019年第7期497-501,共5页Chinese Journal of Diabetes

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015132);江苏省研究生科研与实践创新计划项目(SJCX18_0447)

摘　　要：目的探讨抗阻运动对T2DM患者心血管事件(CVD)发生风险的影响。方法选取2016年3~7月T2DM患者65例,随机分为有氧运动组(AT,n=33)和抗阻运动组(RT,n=32),两组均进行6个月中等强度的运动训练。结果两组WC、肌肉量、同型半胱氨酸(Hcy)运动训练前后差值变化比较,差异有统计学意义(P<0.05或P<0.01)。运动后,RT组肌肉量、FIns和Hcy浓度较运动前改善(P<0.05或P<0.01);AT组WC、WHR、FPG、TC和胱抑素C浓度较运动前降低(P<0.05或P<0.01);两组均能有效改善HDL-C、HbA1c、Framingham危险评分和CVD 10年风险。结论抗阻运动在肌肉量增长和Hcy浓度降低方面具有明显优势,是适合T2DM患者的运动方式,可预防CVD发生。Objective To explore the effects of aerobic and resistance training on cardiovascular disease(CVD)risk indicators in T2 DM patients.Methods 65 T2 DM patients were randomly assigned to 2 groups:aerobic training(AT,n=33)and resistance training(RT,n=32)group. The two groups underwent 6 months of moderate intensity exercise.Results The difference value of WC,muscle mass and Homocysteine(Hcy)concentrations(6 months later-baseline)between 2 groups were significant difference(P<0. 05 or P<0. 01). In RT group,the muscle mass,Fins and Hcy levels were significantly different before and after 6 months intervention(P<0. 05 or P<0. 01). Correspondingly,AT group had significant difference in WC,WHR,FPG,TC and serum cystatin C(Cys-C)before and after training(P<0. 05 or P<0. 01). Both groups can effectively increase HDL-C levels and reduce HbA1 c,Framingham risk scores and CVD 10-year risks.Conclusion Resistance training has obvious advantages in the increase of muscle mass and the decrease of Hcy concentration which may be recommended to prevent CVD.

关 键 词：糖尿病 2型 抗阻运动 有氧运动 心血管风险 

分 类 号：R587.2[医药卫生—内分泌]