病毒模板合成的金属纳米材料及应用  

Virus-Templated Synthesis of Metal Nanomaterials and Their Application

作　　者：杨悦[1] 王珏玉[1] 赵敏[1] 崔岱宗[1] Yue Yang;Jueyu Wang;Min Zhao;Daizong Cui(Northeast Forestry University,Harbin 150040,China)

机构地区：[1]东北林业大学

出　　处：《化学进展》2019年第7期1007-1019,共13页Progress in Chemistry

基　　金：国家自然科学基金项目(No.51678120);中央高校基本科研业务费专项(No.2572019AA19)资助~~

摘　　要：金属纳米材料具有界面效应、量子尺寸效应、宏观量子隧道效应等优异的性能及广泛的应用前景,在目前的研究中备受关注。常用于合成纳米材料的生物模板包括DNA、蛋白质、细菌、真菌、病毒等。而以病毒模板合成的金属纳米材料具有良好的稳定性、分散性及生物相容性,其在催化、光学、电学、磁学、化学。超导等领域有优异的表现。首次利用病毒模板合成金属纳米材料以来,经历了二十年发展历程,合成和分析技术日趋成熟,现由体外应用转向活体靶向成像及诊疗一体化方向发展。本文综述了各类病毒模板合成金属纳米材料合成位置(病毒腔内、外)、合成原理、合成方法、合成影响因素、材料表征,及合成材料在纳米催化、纳米电池、生物医学及医学影像学等领域应用的最新进展,在此基础上展望了研究中尚待解决的问题和未来研究方向。In recent years, metal nanomaterials have been widely used due to their excellent properties, such as interfacial effect, quantum size effect and macroscopic quantum tunneling effect. Biotemplates are often used to synthesize nanomaterials, including DNA, proteins, bacteria, fungi, viruses and so on. The metal nanomaterials, which are synthesized by virus template, compared with other biotemplates, usually have better stability, dispersity and biocompatibility. Moreover, nanomaterials have excellent performances in catalysis, optics, electricity, magnetism, chemistry and superconduction. With nearly 20 years’ development, the technology of nanomaterial synthesis by using virus as template has been gradually matured. Nowadays, research interest is focused on targeted imaging and disease treatment. The object of this review is to discuss the process and the mechanism of nanomaterial biosynthesis by using virus as templates, such as the synthetic sites(inside and outside the virus cavity ), synthesis principles, different synthesis methods, influencing factors and nanomaterials characterization. In addition, the applications of these nanomaterials in different fileds, such as nanocatalysis, nano-batteries, biomedical and medical imaging are discussed. Finally, the problems to be solved in the current research and the development trend of the future research on the synthesis of metal nanomaterials by using virus as template are described.

关 键 词：病毒模板 金属纳米材料 生物合成 生物医学 磁共振成像 

分 类 号：O614[理学—无机化学] O611.4[理学—化学]