明胶基温敏性水凝胶的合成及凝胶性能  

Synthesis and Gel Properties of Gelatin Based Thermo-Responsive Hydrogel

作　　者：隋美玉 刘夕升 赵聪 于跃芹[1] Meiyu Sui;Xisheng Liu;Cong Zhao;Yueqin Yu(College of Chemistry and Molecular Engineering,Key Laboratory of Eco-Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,China)

机构地区：[1]青岛科技大学化学与分子工程学院生态化工教育部重点实验室培育基地

出　　处：《高分子材料科学与工程》2019年第7期13-17,共5页Polymer Materials Science & Engineering

基　　金：国家自然科学基金资助项目(20876081);山东省自然科学基金资助项目(ZR2012BM015)

摘　　要：将具有三螺旋结构的天然高分子明胶改性后引入温敏性水凝胶聚-N-异丙基丙烯酰胺(PNIPAAm)体系中,合成了P(MAGEL-NIPAAm)水凝胶。系统研究了引发剂(APS)、交联剂(BIS)和明胶用量对水凝胶的温敏性、溶胀性和压缩强度的影响,得到水凝胶的最佳合成条件为:MAGEL占单体用量的30%,引发剂APS用量为0.084%,BIS加入量0.12%。水凝胶压缩率达到76.6%,具有良好的韧性;水凝胶形状记忆比均大于96%,形状记忆功能良好。明胶的引入可有效提高水凝胶的生物可降解性、韧性、压缩强度和形状记忆功能,为水凝胶的实际应用提供了理论参考。Gelatin is a well-known biocompatible and biodegradable natural polymer,which has an excellent rigid triple-helical crystalline structure.By introducing maleylgelatin(MAGEL)into the conventional poly(N-isopropyl acrylamide)(PNIPAAm)hydrogel,the P(MAGEL-NIPAAm)hydrogel was synthesized.Thermo-responsive behaviors,equilibrium swelling ratio(SR)and compression strength of hydrogels were investigated,the optimal synthesis conditions of the hydrogel as follows:MAGEL accounts for 30%of the monomer,the initiator APS dosage 0.084%,and the BIS dosage 0.12%.The compression ratio of the P(MAGEL-NIPAAm)hydrogel is 76.6%,and the shape memory ratio of hydrogel is more than 96%,indicating excellent hydrogel toughness.The composite hydrogel with relatively high water content possesses a good compressive strength,tensile strength and stretrability,which would expand the scope of the PNIPAAm hydrogel applications.

关 键 词：马来酰化明胶 N-异丙基丙烯酰胺 温敏性 压缩强度 形状记忆 

分 类 号：TQ427.2[化学工程]