葶苈子、牵牛子、汉防己“利水三味”在钱氏葶苈丸中的配伍应用辨析  

Differentiation and analysis of the compatibility application of "Lishui Sanwei" of Lepidium seed, Semen pharbitidis, and Stedhania tetrandra in Qian′s Tingli Pills

作　　者：殷越[1] 武文杰 王清玉 朱泽华 范诗琪 刘畅 YIN Yue;WU Wenjie;WANG Qingyu;ZHU Zehua;FAN Shiqi;LIU Chang(School of Basic Medicine,Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin 150040,China;Graduate School,Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学基础医学院,黑龙江哈尔滨150040 [2]黑龙江中医药大学研究生院,黑龙江哈尔滨150040

出　　处：《中国医药导报》2019年第21期151-154,162,共5页China Medical Herald

基　　金：黑龙江省博士后资助项目(LBH-Z14197);黑龙江省中医药科研项目(ZHY12-Z097)

摘　　要：本文借助中华医典软件系统和古籍文献资料库及中国知网、万方数据库,以“葶苈(子)”“(黑)牵牛(子)”“防己”为关键词,查阅并梳理不同时代医药著作中记载的三药合用的方剂72首,其中记载方名为葶苈丸的著作最多,共15部。通过梳理方剂学发展脉络,从方剂组成及药量变化的层面得出初步结论,即钱氏葶苈丸从《太平圣惠方》中化裁而来,并在《圣济总录》中加以变化,可信度高。从药物功效、性味特点、归经及剂型与煎服法等不同角度剖析葶苈子、牵牛子、汉防己三味具有利水功效的中药在钱氏葶苈丸中的配伍关系,并借助现代药理学研究进展,挖掘中医古籍经典方剂的临床应用价值,以期为利用现代科学技术手段开展的中药性味、功效的物质基础研究提供理论参考和依据。With the help of Chinese Medical Code Software System and the Ancient Literature Database and China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,the"Draba nemorosa,Pharbitis nil(Linn.)Choisy,Stephania tetrandra S.Moore"as the key words,this article looked up and sorted out 72 prescriptions in which the three Chinese herbs were combined as described in the medical books of the different eras.Among them,the books recording the Tingli Pills had the largest number,with the total number 15.Through sorting out the development of prescriptions,the preliminary conclusions were drawn from the composition of the prescriptions and the changes in the doses.Qian′s Pills were transferred from the Peaceful Holy Benevolent Prescriptions and transformed in the General Medical Collection of Royal Benevolence,with high credibility.Through the different effects of drug efficacy,gender taste characteristics,channel tropism,dosage forms and decoction methods,the compatibility of Chinese herbal medicines in Qian′s Pills with scorpion venom,venom and Chinese medicinal herbs were analyzed,and research progress of modern pharmacology was applied to further digging up of the clinical application value in classical prescriptions of ancient Chinese medicine,and provide theoretical reference and basis for the research of substances of Chinese medicine taste and efficacy carried out by modern scientific and technological means.

关 键 词：利水药 钱氏葶苈丸 药物配伍 应用辨析 

分 类 号：R289.1[医药卫生—方剂学]