帕金森病多巴胺失调综合征的研究进展  

Research progress of dopamine dysregulation syndrome in Parkinson disease

作　　者：段理人 李俊英[1] 彭蓉[1] Duan Liren;Li Junying;Peng Rong(Neurology Department, West China Hospital, Sichuan University, Chengdu 610041, China)

机构地区：[1]四川大学华西医院神经内科,成都610041

出　　处：《神经疾病与精神卫生》2019年第5期527-532,共6页Journal of Neuroscience and Mental Health

摘　　要：多巴胺失调综合征(DDS)是一种由于对多巴胺能药物成瘾而产生一系列精神行为异常表现的临床综合征,最常见于使用多巴胺能药物替代治疗的帕金森病患者。现从危险因素、发病机制、临床表现、诊断评估、治疗及预后等多个方面阐述帕金森病DDS的研究进展。Dopamine dysregulation syndrome (DDS) is a clinical syndrome that produces a series of psychological and behavioral abnormalities due to the addiction to dopaminergic drugs, most commonly found in patients with Parkinson disease who are under dopaminergic replacement therapy. This article reviews the research progress of dopamine dysregulation syndrome in Parkinson disease in terms of the risk factors, pathogenesis, clinical manifestations, diagnosis, evaluation, treatment, and prognosis.

关 键 词：帕金森病 多巴胺能药物替代治疗 多巴胺失调综合征 综述 

分 类 号：R595.505[医药卫生—内科学]