名医群体辨治慢性前列腺炎方药规律探析  

The analysis of the prescription rules in treating chronic prostatitis by TCM differentiation from famous doctors

作　　者：闵杰 刘慧英[1] 贺慧娥[1] 贺勇凯 王帅[1] 朱治亚 张仲楠 高瑞松 林群芳[2] 周青[2] Min Jie

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]湖南中医药大学第一附属医院,湖南长沙410000

出　　处：《中医临床研究》2019年第17期6-10,共5页Clinical Journal Of Chinese Medicine

基　　金：国家自然科学基金(No.81573988);湖南科技厅项目资助(No.S2015F102P010)

摘　　要：目的:通过分析国家级名医群体辨治慢性前列腺炎的方药规律,为临床慢性前列腺炎的治疗组方用药提供启发和思路。方法:检索中国知网数据库,筛选出建库至2018年2月主治病证为"慢性前列腺炎"文献,统计处方与用药。采用中医传承辅助系统(V2.5)软件,分析当代名老中医治疗慢性前列腺炎经验中各种药物的使用频次及药物之间的关联规则。结果:检索得到119位第一至六批全国名老中医慢性前列腺炎文献共计420篇,涉及256首古代方剂,241味中药。单味中药使用频次前10位的由高到低依次为:茯苓、车前子、黄柏、当归、泽泻、赤芍、牛膝、王不留行、牡丹皮、败酱草。药物归经由多到少依次为:肝>肾>脾>胃>心>肺>膀胱>大肠>小肠>胆。药物在"五味"中所占比重由多到少依次为:甘、苦、辛、涩、酸、咸。药物在"四气"中所占比重由高到低依次为:寒、温、平、凉、热。总结显性常用药物47个,处方规则分析19个,药物间核心组合模式多见女贞子、牡丹皮等药物与生地黄、黄柏等关联。结论:慢前列腺炎用药的规律多以清热利湿、活血化瘀为主,补肾固本为辅的治法。论治多虚实同治、补泻兼顾,用药多处方灵活、配伍严谨。Objective: The prescriptions of treating prostatitis were analyzed by the national famous doctors, to provide the methods of medicine application and new thinking and experience. Methods: CNKI database(From its building to september 2018) with the key words prostatitis were searched. And all prescriptions and medicine were analyzed. The software(TCM inheritance support system V2.5) was used to construct the database, and analyze the drugs, the combination rules, the core combination and the new methods. Results: A total of 420 literatures were selected, including 256 ancient prescriptions and 241 TCM medicine. The results showed that the medicine listed with usage frequency from high to low was Fuling(茯苓), Cheqianzi(车前子), Huangbo(黄柏), Danggui(当归), Zexie(泽泻), Chishao(赤芍), Niuxi(牛膝), Wangbuliuxing(王不留行), Mudanpi(牡丹皮), Baijiangcao(败酱草). Channel tropism of medicines listed by more to least was liver, kidney, spleen and stomach, heart, lung, bladder, colorectal, small intestine, bile. Medicines listed by proportion in five flavors from high to low were sweet, bitter, pungent, astringent, sour, salty. Medicines listed by proportion in Siqi(四气) from high to low were Han(寒), Wen(温), Ping(平), Liang(凉), Re(热). There were 47 and 19 prescriptions applied frequency. The core combination among medicines was Nvzhenzi(女贞子) and Mudanpi, Shengdihuang(生地黄) and Huangbo oigustrum oucidum with moutan and radix rehmanniae with phellodendron. Conclusion: The law of medicine in treating chronic prostatitis is mainly based on Qingre Lishi(清热利湿) and Huoxue Huayu(活血化瘀), Bushen Guben(补肾固本). The disease was treated by Xushi Tongzhi(虚实同治), Buxie Jiangu(补泻兼顾).

关 键 词：前列腺炎 方药规律 名医群体 中医传承辅助系统 

分 类 号：R697.33[医药卫生—泌尿科学]