儿童肌酸激酶升高病因分析  

Etiology of Creatine Kinase Elevation in Children

作　　者：聂文莎 王尚昆[1] 杨家武[1] 余凯 袁廷运 李银 NIE Wen-sha;WANG Shang-kun;YANG Jia-wu;YU Kai;YUAN Ting-yun;LI Yin(Department of Respiratory and Critical Diseases, Kunming Children's Hospital, Kunming, Yunnan Province, 650000 China)

机构地区：[1]昆明市儿童医院呼吸与危重症科

出　　处：《系统医学》2019年第13期192-194,共3页Systems Medicine

摘　　要：肌酸激酶主要存在于脑组织、心肌及骨骼肌中,主要包括3种同工酶:CK-BB、CK-MB及CK-MM.一般情况下,正常人血清中绝大部分均是CK-MM,少部分是CK-MB,极少量是CK-BB.一般肌细胞内肌酸激酶含量最多,如血清中肌酸激酶含量出现上升,则说明已有或正在出现肌损伤.该文对儿童肌酸激酶升高病因进行了分析,详细阐述了高CK血症的鉴别诊断及诊断思路,以期为更好的防治儿童高CK血症提供一些参考依据.Creatine kinase mainly exists in brain tissue, myocardium and skeletal muscle, including three isoenzymes: CK-BB, CK-MB and CK-MM. In general, most of the serum of normal people is CK-MM, a small part is CK-MB, and a very small amount is CK-BB. Generally, the content of creatine kinase in muscle cells is the highest. If the content of creatine kinase in serum increases, it indicates that muscle injury has occurred or is occurring. In this paper, the etiology of increased creatine kinase in children was analyzed, and the differential diagnosis and diagnostic ideas of hyperck disease were elaborated, so as to provide some reference basis for better prevention and treatment of hyper-CK disease in children.

关 键 词：肌酸激酶 高CK血症 诊断 

分 类 号：R725.1[医药卫生—儿科]