不完全川崎病与典型川崎病临床对比分析  

Clinical Comparative Analysis of Incomplete Kawasaki Disease and Complete Kawasaki Disease

作　　者：杨洁[1] 李文玲[1] 张欧[1] YANG Jie;LI Wenling;ZHANG Ou(Kunming Children’s Hospital,Kunming 650032,China)

机构地区：[1]昆明市儿童医院

出　　处：《中国医学创新》2019年第21期18-21,共4页Medical Innovation of China

摘　　要：目的:分析不完全川崎病(IKD)与典型川崎病(CKD)的临床特征、实验室资料、超声心电图检查结果,提高川崎病(KD)尤其是IKD的诊断水平。方法:选取2015年12月-2017年12月于本院住院治疗的265例KD患者,其中CKD 152例、IKD 113例,对其进行回顾性资料对比分析。结果:两组性别、年龄及结膜充血、卡疤红肿、无菌性脓尿发生率比较,差异均无统计学意义(P>0.05),其中IKD组≤1岁者33.63%,高于CKD组的12.50%(P<0.05);IKD组皮疹、唇口黏膜变化、四肢变化、淋巴结肿大的发生率均低于CKD组(P<0.05);两组实验室指标比较,差异无统计学意义(P>0.05);IKD组冠状动脉瘤(CAA)、冠状动脉改变发生率均高于CKD组(P<0.05)。结论:IKD临床表现不典型,易导致诊断治疗延迟,易发生冠状动脉损害,故应重视相关的临床表现及实验室资料,尽早行超声心动图检查,及时治疗,改善预后。Objective:To analyse the clinical features,laboratory data and ECG findings of incomplete Kawasaki disease(IKD)and complete Kawasaki disease(CKD),so as to improve the diagnostic level of kawasaki disease(KD),especially IKD.Method:A total of 265 patients with KD hospitalized in our hospital from December 2015 to December 2017 were selected,included 152 cases of CKD and 113 cases of IKD,the data were retrospectively analyzed.Result:The gender,age and incidence of conjunctival congestion,scar redness and swelling and aseptic pyuria between two groups were compared,the differences were not statistically significant(P>0.05),among them,33.63% in IKD group were younger than 1 year old,which was higher than 12.50% in CKD group(P<0.05).The incidence of skin rash,lip and mouth mucosal changes,limb changes and lymph node enlargement in IKD group were lower than those of CKD group(P<0.05).The laboratory indexes of two groups were compared,the differences were not statistically significant(P>0.05).The incidence of coronary artery aneurysm(CAA)and coronary artery changes in IKD group were higher than those of CKD group(P<0.05).Conclusion:IKD clinical performance is not typical,it is easy to cause delayed diagnosis and treatment,and is prone to coronary artery damage,so it is necessary to pay attention to related clinical manifestations and laboratory data,perform echocardiography as soon as possible,treat it in time,and improve prognosis.

关 键 词：不完全川崎病 典型川崎病 临床特征 

分 类 号：R725.4[医药卫生—儿科]