大气压固体分析探头离子化技术在饮用水中乐果测定的应用研究  

Application of atmospheric-pressure solids analysis probe-triple quadrupole mass spectrometry technique to determination of dimethoate in drinking water

作　　者：刘斌[1] 赵慧琴[1] 杨辉 王浩然 LIU Bin;ZHAO Hui-qin;YANG Hui;WANG Hao-ran(Qinhuangdao Municipal Center for Disease Control and Prevention,Qinhuangdao,Hebei 066000,China)

机构地区：[1]秦皇岛市疾病预防控制中心

出　　处：《实用预防医学》2019年第8期944-946,共3页Practical Preventive Medicine

基　　金：秦皇岛市重点研发计划科技支撑项目(项目编号:201703A191);秦皇岛市科技支撑项目(201601B043)

摘　　要：目的建立生活饮用水中乐果的大气压固体分析探头离子源-串联质谱测定方法。方法水样用微量移液器直接上样,通过大气压固体分析探头离子源离子化,在大气压化学电离正离子模式下以多反应监测方式检测。结果乐果线性范围为1.5~100.0μg/L,相关系数为0.999 7,检出限为0.5μg/L,加标回收率为73.4%~85.7%,相对标准偏差为9.4%~15.3%。结论大气压固体分析探头离子化技术与串联质谱联用,无需样品前处理和色谱分离即可对样品进行测定,分析速度快、灵敏度高、准确性好,适用于生活饮用水中乐果的测定。Objective To establish a method for the determination of dimethoate in drinking water by atmospheric pressure solids analysis probe-triple quadrupole mass spectrometry(ASAP-MS/MS). Methods Water samples were added to the probe by pipette, detected by mass spectrometer in positive mode using multiple reaction monitoring. Results The linear range of dimethoate was 1.5-100.0 μg/L, the correlation coefficient was 0.9997, and the limit of detection was 0.5 μg/L. The average recovery of standard addition was 73.4%-85.7%, and the relative standard deviation was 9.4%-15.3%. Conclusions The proposed ASAP-MS/MS technique can be a powerful tool for sample detection without any sample pretreatment and chromatographic separation. This technique has the advantages of rapidity, high sensitivity and accuracy, and it is suitable for the determination of dimethoate in drinking water.

关 键 词：乐果 生活饮用水 检测 大气压固体分析探头离子源 

分 类 号：R123.1[医药卫生—环境卫生学]