兰州市儿童支气管哮喘的特点及相关危险因素的调查研究  

Investigation on Characteristics and Risk Factors of Bronchial Asthma in Children in Lanzhou Gity

作　　者：豆莉[1] 姜彦斌 马建丽[1] DOU Li;JIANG Yanbin;MA Jian-li(The Second People’s Hospital of Lanzhou,Lanzhou,730030,China)

机构地区：[1]甘肃省兰州市第二人民医院,兰州730030 [2]兰州大学循证医学中心,兰州730000 [3]兰州大学第二临床医学院,兰州730000

出　　处：《中国初级卫生保健》2019年第8期56-58,70,共4页Chinese Primary Health Care

基　　金：兰州市科技计划项目(2016-2-12)

摘　　要：目的探讨兰州市儿童支气管哮喘的危险因素,为哮喘的防治提供参考依据。方法采用病例对照的研究方法,收集2017年3月-12月在兰州市第二人民医院儿科住院诊治的儿童哮喘患者及非哮喘患者共182例,病例组和对照组患儿按照1∶1进行配比,以问卷形式调查,对所有研究因素进行单因素和多因素logistic回归分析,筛选出与哮喘相关的危险因素。结果单因素logistic回归分析结果显示:一、二级亲属患过支气管哮喘,且有药物食物粉尘过敏史、3~6个月和0.5~1年内使用抗生素,既往诊断为湿疹、荨麻疹、气管/支气管炎等均为支气管哮喘的危险因素;多因素logistic回归分析显示:3~6个月和0.5~1年内使用抗生素、既往诊断为湿疹、毛细支气管炎和食物过敏史等均为支气管哮喘的独立危险因素。结论影响甘肃省兰州市儿童哮喘发病相关的危险因素较多,而且哮喘患者及其家属对该疾病的认知、自我监管知识均较为欠缺,今后需要进一步加大力度开展哮喘知识的科普教育,避免哮喘的诱发因素,从而降低哮喘的发病率和病死率。OBJECTIVE To explore the correlative causes of bronchial asthma in children in Lanzhou Gity,and to provide evidence for preventing bronchial asthma METHODS Group case-control method was adopted to analyze the correlative causes of bronchial asthma in children. The matched case-control study was performed in 91 patients with asthma and 91 patients of matched controls. Logistic regression analysis was used for correlation analysis to select the risk factors correlated with a sthma. RESULTS The results of single-factor logistic regression analysis indicated the first and second degree relatives suffering from bronchial asthma hawing a history of drug food dust allergy,hawing antibiotics within 3-6 months and 0.5~1 years,history of eczema,history of urticarial,history of tracheitis/bronchitis,are the risk factors The results of multiple-factor Logistic regression analysis indicate 3-6 months and 0 5-1 years of antibiotics,history of eczema,history of bronchiolitis,were all independent risk factors CONCLUSION There are a lot of risk factors which affect childhood asthma in Lanzhou. The awareness of bronchial asthma and the self-regulation were low among the patients. it is suggested to pay attention to the health education,and avoid the risk factors to reduce morbidity and fatality.

关 键 词：儿童 支气管哮喘 危险因素 病例对照研究 LOGISTIC 回归分析 

分 类 号：R1-9[医药卫生—公共卫生与预防医学]