妊娠期心电图短P-R间期的形成机制与临床价值分析  

Formation mechanism of short P-R interval in ECG during pregnancy and its clinical value

作　　者：陶硕 杨应清 张文荟 TAO Shuo;YANG Ying-qing;ZHANG Wen-hui(ECG Room,Mental Health Center of Guangyuan City,Guangyuan,Sichuan,628000,China)

机构地区：[1]广元市精神卫生中心心电图室

出　　处：《心血管康复医学杂志》2019年第4期495-497,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨妊娠中晚期心电图短P-R间期形成机制及短P-R间期临床价值。方法:我院电生理科进行心电图检查的妊娠中晚期孕妇100例,根据心电图检查结果分为短P-R间期组和心电图正常组,观察比较两组孕妇24h心率变异性、产后12个月产妇一般情况及新生儿情况。结果:与心电图正常组比较,短P-R间期组孕妇的24h正常RR间期标准差(SDNN)[(120.6±28.7)ms比(90.6±25.8)ms]、24h每5min正常RR间期标准差的平均值(SDNNIndex)[(115.6±27.6)ms比(79.8±25.9)ms]、相邻正常RR间期差值的均方根(rMSSD)[(38.8±13.1)ms比(28.7±12.5)ms]、相邻正常RR间期之差>50ms的心搏数占24h总RR间期数的百分比(PNN50)[(15.6±10.3)%比(7.9±5.4)%]、极低频(VLF)[(1937.7±734.9)Hz比(996.7±114.2)Hz]、低频(LF)[(579.8±256.0)Hz比(285.7±134.7)Hz]及高频(HF)[(341.3±185.3)Hz比(199.6±146.8)Hz]水平均显著降低(P均=0.001);两组新生儿情况和孕妇产后12个月的高血压、贫血、心动过速、心衰及短P-R间期发生率比较无统计学意义(P均>0.05)。结论:中晚期孕妇出现短P-R间期是一种相对正常的生理现象,为心率变异变化,其形成机制可能与妊娠期交感神经兴奋性增强有关,对新生儿和分娩后产妇无显著影响。Objective: To explore formation mechanism of short P-R interval in ECG during mid-late pregnancy and its clinical value. Methods: A total of 100 mid-late pregnant women,who received ECG examination in our department of electrophysiology,according to ECG results were divided into short P-R interval group (n=50) and normal ECG group (n=50). The 24h heart rate variability (HRV),general condition of pregnant women on 12 months after childbirth and the newborn condition were observed and compared between two groups. Results: Compared with normal ECG group,there were significant reductions in standard deviation of normal to normal RR intervals calculated over the 24h period (SDNN)[(120.6±28.7)ms vs.(90.6±25.8)ms],SDNN Index [(115.6±27.6)ms vs.(79.8±25.9)ms],root-mean square of differences between successive normal to normal intervals (rMSSD)[(38.8±13.1)ms vs.(28.7±12.5)ms],adjacent normal RR interval difference > 50ms stroke accounted for a percentage of 24h total RR interval (PNN50)[(15.6±10.3)% vs.(7.9±5.4)%],very low frequency (VLF)[(1937.7±734.9)Hz vs.(996.7±114.2)Hz],low frequency (LF)[(579.8±256.0)Hz vs.(285.7±134.7) Hz] and high frequency (HF)[(341.3±185.3) Hz vs.(199.6±146.8)Hz] in short P-R interval group, P =0.001 all. There were no significant difference in newborn condition,incidence rates of hypertension,anemia,tachycardia,heart failure and short P-R interval on 12 months after childbirth between two groups, P >0.05 all. Conclusion: Occurrence of short P-R interval is a relatively normal physiological phenomenon in mid-late pregnant women. It's heart rate variability change. Its mechanism is related to enhanced sympathetic excitability during pregnancy,and possesses no significant influence on newborn and women after childbirth.

关 键 词：妊娠 心电描记术 自主神经系统 

分 类 号：R540.41[医药卫生—心血管疾病]