MR高分辨率管壁成像与超声评价颈动脉斑块负荷的对比研究  

Carotid plaque load evaluation:comparison high resolution MR imaging with ultrasound

作　　者：崔雪花 叶玉芳[2] 单春辉 焦荣红[3] 陈英敏[2] 张淑倩[2] Cui Xuehua;Ye Yufang;Shan Chunhui;Jiao Ronghong;Chen Yingmin;Zhang Shuqian(Department of Neurosurgery,Second Hospital,Hebei Medical University,Shijiazhuang 050000,China;Department of Medical Imaging,Hebei General Hospitial,Shijiazhuang 050051,China;Department of Ultrasound,Hebei General Hospitial,Shijiazhuang 050051,China)

机构地区：[1]河北医科大学第二医院神经外科,石家庄050000 [2]河北省人民医院医学影像科,石家庄050051 [3]河北省人民医院超声科,石家庄050051

出　　处：《中华放射学杂志》2019年第8期690-693,共4页Chinese Journal of Radiology

基　　金：河北省医学适用技术跟踪项目(GL201707).

摘　　要：目的对比分析MR高分辨率管壁成像(HR-VWI)和超声评价颈动脉斑块负荷的价值。方法前瞻性收集2016年8月至2017年1月河北省人民医院,常规体检超声检出的21例颈动脉分叉区斑块患者,分别接受HR-VWI和超声检查。对图像质量≥3分且两种检查匹配的斑块,在HR-VWI图像上测量斑块厚度(PT)、管腔面积(LA)、管壁面积(WA)、血管总面积(TVA),计算管壁标准化指数(NWI)。采用独立样本t检验(正态分布方差齐数据)或非参数Wilcoxon检验(偏态分布或方差不齐数据)比较不同检查方法测得的斑块负荷指标,评价两种检查方法所得斑块负荷指标的相关性采用Pearson检验。结果共有45个斑块被两种方法同时检出并符合匹配要求。采用MR HR-VWI和US测得的PT、LA、WA、TVA和NWI差异均无统计学意义(P>0.05)。采用两种方法测得的PT、LA、WA、TVA和NWI均具有相关性(r值分别为0.83、0.85、0.32、0.83和0.59,P均<0.05)。结论HR-VWI在评价颈动脉斑块负荷方面与US效果相近。Objective To compare the image quality produced by MR high resolution vessel wall imaging (HR-VWI) and ultrasound (US) in evaluating carotid plaque load.Methods This prospective study enrolled 21 patients with carotid plaques undergoing HR-VWI and subsequent 2D US between August 2016 to January 2017 in Hebei General Hospitial.The plaque thickness (PT),lumen area (LA),wall area (WA) and total vessel area (TVA) of the plaques were measured and normalized wall index (NWI) was calculated on both HR-VWI images and US for those plaques with image quality score≥3 and matching between the two methods.The plaque load index was compared by using the independent sample t test or the non-parametric Wilcoxon test,and the correlation between the indexes was based on the Pearson test.Results Forty-five carotid plaques were matched with HR-VWI and US.There was no significant difference in PT,LA,WA,TVA and NWI detected by HR-VWI and ultrasound (P>0.05).The parameters measured by two methods were correlated (r values were 0.83,0.85,0.32,0.83 and 0.59,P<0.05).Conclusion There is a good consistency between HR-VWI and conventional ultrasound in the measurement of carotid plaque load.

关 键 词：颈动脉血栓形成 动脉硬化 磁共振成像 超声 

分 类 号：R543.4[医药卫生—心血管疾病] R445[医药卫生—内科学]