上海市华漕社区1918例脑卒中高危人群同型半胱氨酸检测与分析  

Detection and analysis of homocysteine examination in 1 918 high risk population of stroke in Huacao Community,Shanghai

作　　者：易强[1] 尤佳恺 孙兰[1] 赵慧蓝 杨圣元[1] YI Qiang;YOU Jiakai;SUN Lan;ZHAO Huilan;YANG Shengyuan(Huacao Community Center for Health Service Shanghai,Shanghai 201107,China)

机构地区：[1]上海市闵行区华漕社区卫生服务中心

出　　处：《公共卫生与预防医学》2019年第4期107-109,共3页Journal of Public Health and Preventive Medicine

摘　　要：目的了解上海市闵行区华漕社区脑卒中高危人群同型半胱氨酸(Hcy)水平,分析其影响因素,为预防脑卒中提供科学依据。方法对上海市闵行区华漕社区1918名50岁以上当地户籍居民进行脑卒中高危人群筛查问卷,清晨空腹抽血检查血脂、血糖、Hcy浓度、B超检查颈动脉斑块。问卷数据及检查结果整理后导入SPSS20.0进行统计分析。结果Hcy浓度升高脑卒中高危人群中有劲动脉斑块人数占比53.16%,高于Hcy浓度正常的脑卒中高危人群;脑卒中高危人群随着年龄增加,Hcy浓度均值也随之增大;1918名脑卒中高危人群中男性、有吸烟史、有高血压史、有血脂史、有脑卒中史组别的Hcy平均浓度高于女性、无吸烟史、无高血压史、无血脂史、无脑卒中史(P<0.05)差异有统计学意义。结论筛查并发现脑卒中高危人群是预防脑卒中的前提,对脑卒中高危人群中特别是男性,有吸烟、高血压、高血脂、既往有脑卒中史人群进行宣传教育并干预是关键,降低Hcy水平是有效减少并预防脑卒中发生的有效措施之一。Objective To understand the level of homocysteine (Hcy) in high-risk populations of stroke in Huacao community and to analyze the influencing factors in order to provide scientific evidence for prevention of stroke. Methods A total of 1 918 residents over 50 years old in Huacao community were screened for high-risk stroke. Blood samples were taken on an empty stomach in the morning to check blood lipids, blood sugar, Hcy concentration, and B-ultrasound for carotid plaque. Questionnaire data and test results were sorted and imported into SPSS 20.0 for statistical analysis. Results The concentration of Hcy was higher in the group with high-risk of stroke, People with carotid plaque accounted for 53.16% in the high-risk group with high Hc concentration, which was higher than the high-risk group with normal Hcy concentration. The high-risk group with stroke and the mean value of Hcy concentration both increased with age. Among 1 918 stroke high risk population, the average Hcy concentration was higher in the males, and in people with smoking history, history of hypertension, history of blood lipids, and history of stroke than in the females, and in people with no smoking history, no history of hypertension, and no history of stroke. There was no significant difference in the history of no blood lipids and no stroke history ( P <0.05). Conclusion Screening and finding the high-risk stroke people were the premise of preventing stroke. It is the key to the high-risk group of stroke patients, especially men, who have smoking, high blood pressure, high blood lipids, and previous history of stroke. Reducing Hcy levels is one of the effective measures to effectively reduce and prevent stroke.

关 键 词：脑卒中高危人群 同型半胱氨酸 影响因素 

分 类 号：R18[医药卫生—流行病学] R743.3[医药卫生—公共卫生与预防医学]