碘诱导的醛糖与o-氨基苯甲酰胺的氧化缩合合成糖基喹唑啉酮（英文）  

Synthesis of Aldo-quinazolinones by Iodine-Induced Oxidative Condensation of Aldoses and o-Aminobenzamides

作　　者：琚欢欢 孙佳婧 李小六 陈华 Ju Huanhuan;Sun Jiajing;Li Xiaoliu;Chen Hua(Key Laboratory of Chemical Biology of Hebei Province,College of Chemistry and Environmental Science,Hebei University,Baoding 071002)

机构地区：[1]河北大学化学与环境科学学院河北省化学生物学重点实验室

出　　处：《有机化学》2019年第7期2018-2025,共8页Chinese Journal of Organic Chemistry

基　　金：Project supported by the National Natural Science Foundation of China(Nos.21772031,21372060)~~

摘　　要：以不保护的单/双糖和邻氨基苯甲酰胺为原料,通过碘诱导的氧化缩合一锅法反应,合成了系列糖基喹唑啉酮衍生物,产率30%~80%,为该类化合物的合成提供了一个有效方法.碘的用量对该反应有重要的影响.A series of aldo-quinazolinones were synthesized by a one-pot iodine-induced oxidative condensation of the unprotected mono-/di-saccharides and o-aminobenzamides in the yields of 30%~80%,providing an effective protocol for the preparation of aldo-quinazolinones.The amount of iodine has an important effect on the reaction.

关 键 词：糖基喹唑啉酮 氧化缩合 碘诱导 

分 类 号：O621.3[理学—有机化学]