可吸收修复胶原联合银离子敷料治疗供皮区创面的疗效  

Absorbable repair collagen combined with silver ion dressing in the treatment of donor site wounds

作　　者：邹晓防 肖孟景 李宝龙 吴世建 李斌 ZOU Xiaofang;XIAO Mengjing;LI Baolong;WU Shijian;LI Bin(Department of Burns and Plastic Surgery, Air Force General Hospital, Beijing 100142, China)

机构地区：[1]空军特色医学中心烧伤整形科

出　　处：《武警医学》2019年第7期576-579,共4页Medical Journal of the Chinese People's Armed Police Force

基　　金：北京市科技计划项目(Z161100000116056)

摘　　要：目的观察可吸收修复胶原联合银离子敷料治疗供皮区创面的临床效果。方法选取2016-07至2018-12医院收治的100例自体皮移植患者,随机分为治疗组和对照组,每组50例,治疗组采用可吸收修复胶原联合银离子敷料治疗供皮区创面,对照组采用传统凡士林纱布治疗。观察供皮区创面换药时疼痛程度、创面感染率、愈合时间,以及创面愈合后瘢痕指标评定。结果治疗组供皮区创面换药时疼痛分数在术后3、6、9 d分别为6. 24±2. 23,4. 13±2. 37,1. 49±1. 31,显著低于对照组的7. 73±2. 14,5. 24±1. 59,2. 43±1. 66(P <0. 05);治疗组供皮区创面感染率为2%,较对照组14%显著降低(P <0. 05);治疗组创面愈合时间明显短于对照组(P <0. 05);治疗组创面愈合后3、6、9个月温哥华瘢痕量表评分较对照组显著降低,差异均有统计学意义(P <0. 05)。结论可吸收修复胶原联合银离子敷料治疗供皮区创面相比于传统凡士林纱布治疗是一种更优越的方式,适合临床推广使用。Objective To observe the clinical effect of absorbable collagen repair combined with silver ion dressing in the treatment of skin donor wounds. Methods One hundred patients receiving autologous skin grafting were randomly divided into the treatment group and control group, with 50 cases in each. The treatment group received absorbable repair collagen combined with silver ion dressing to treat the donor site wounds, while the control group received traditional vaseline gauze treatment. The degree of pain during dressing change, wound infection rate, wound healing time, and the scar index after wound healing were observed.Results The pain during wound dressing in the treatment group was significantly less acute than in the control group ( 6.24±2.23,4.13±2.37,1.49±1.31 vs 7.73±2.14,5.24±1.59,2.43±1.66 at 3, 6, 9 days post surgery). The wound infection rate in the treatment group was 2%, which was significantly lower than 14% in the control group. The wound healing time was significantly reduced in the treatment group as compared to the control group. The degree of scar hyperplasia after wound healing was remarkedly ameliorated. Vancouver scar scores were 3.34±3.27,3.89±3.48 and 3.63±4.87 at 3, 6, 9 months post wound healing in the treatment group vs. 8.31±3.75,9.32±4.27 and 8.06±4.98 in the control group.Conclusions The absorbable repair collagen combined with silver ion dressing for the treatment of donor site wounds is superior to the traditional vaseline gauze treatment, which should be made more accessible.

关 键 词：可吸收修复胶原 银离子敷料 自体皮移植 供皮区创面 

分 类 号：R644[医药卫生—外科学]