组织印片DNA倍体对胃癌诊断、预后评估价值  

The Value of Tissue Print DNA Ploidy in the Diagnosis and Prognosis of Gastric Cancer

作　　者：熊利芬 朱文成 XIONG Lifen;ZHU Wencheng(Department of Gastroenterology, ThirdPeople's Hospital of Hubei Province, Wuhan Hubei 430033, China)

机构地区：[1]湖北省第三人民医院消化内科

出　　处：《中国继续医学教育》2019年第23期57-59,共3页China Continuing Medical Education

基　　金：湖北省卫生厅科研项目（JX6B86）

摘　　要：目的分析组织印片中DNA倍体的类型对胃癌的诊断以及预后的影响。方法选取有150例胃癌患者的标本,制成组织印片,再取周围非肿瘤组织制成印片,通过全自动细胞图谱分析系统进行分析。研究DNA异倍体率与患者的年龄、性别以及肿瘤的大小、肿瘤的分化程度还有癌淋巴结转移以及肿瘤细胞浸润的深度的关系。结果胃癌DNA异倍体率与年龄性别、肿瘤大小、浸润的深度没有明显关系;与肿瘤的分化程度、胃癌淋巴结的转移有明显关系。结论组织印片中DNA倍体分析能够帮助对患者胃癌的诊断以及预后。Objective To analyze the influence of the type of DNA ploidy in tissue printing on the diagnosis and prognosis of gastric cancer. Methods A specimen of 150 patients with gastric cancer was selected and made into tissue prints. The surrounding non-tumor tissues were then printed and printed by automated cell mapping system. The relationship between the rate of DNA aneuploidy and the age, sex and size of the tumor, the degree of tumor differentiation, and the depth of cancer lymph node metastasis and tumor cell infiltration were studied. Results The DNA aneuploidy rate of gastric cancer had no significant relationship with age, sex and tumor size;it was related to the degree of tumor differentiation;it was related to lymph node metastasis of gastric cancer, and had no relationship with the depth of invasion. Conclusion DNA ploidy analysis in tissue printing can help diagnose and prognose gastric cancer in patients.

关 键 词：组织印片 DNA倍体 胃癌 诊断 预后 评估价值 

分 类 号：G642[文化科学—高等教育学]