右美托咪定与瑞芬太尼对手汗症患者的麻醉效果比较  

Anaesthetic effect comparison of Dexmedetomidine and Remifentanil in patients with palmar hyperhidrosis

作　　者：郑思屏 ZHENG Si-ping(Department of Anesthesiology,the First Hospital in Huizhou City,Guangdong Province,Huizhou 516000,China)

机构地区：[1]广东省惠州市第一人民医院麻醉科

出　　处：《中国当代医药》2019年第23期113-116,共4页China Modern Medicine

基　　金：广东省惠州市科技计划项目(170520181743180)

摘　　要：目的研究右美托咪定与瑞芬太尼对手汗症患者的麻醉效果。方法选取2017年8月~2018年7月我院收治的50例手汗症患者作为研究对象,按照随机数字表法将其分为对照组和观察组,每组各25例。两组患者均采用喉罩全身麻醉,对照组采用瑞芬太尼麻醉,观察组采用右美托咪定麻醉。比较两组患者的临床相关指标、麻醉效果、视觉模拟疼痛量表(VAS)评分以及住院时间。结果观察组患者手术开始后15min、手术结束后30min的心率慢于对照组,差异有统计学意义(P<0.05);观察组患者手术开始后15min、手术开始后30min的呼吸频率高于对照组,差异有统计学意义(P<0.05);观察组患者手术开始后15min、手术开始后30min的潮气末二氧化碳分压低于对照组,差异有统计学意义(P<0.05);观察组患者手术开始后15min、手术开始后30min、手术结束后30min时的平均动脉压均低于对照组,差异有统计学意义(P<0.05);两组患者不同时间点的血氧饱和度比较,差异无统计学意义(P>0.05);观察组患者的自主恢复时间、拔管时间、完全苏醒时间以及住院时间均短于对照组,差异有统计学意义(P<0.05);观察组患者的VAS评分低于对照组,差异有统计学意义(P<0.05)。结论在手汗症患者采用喉罩全身麻醉下,胸腔镜交感神经链切除术治疗中采用右美托咪定的麻醉效果比瑞芬太尼更加优越。Objective To study the anesthetic effect of Dexmedetomidine and Remifentanil in patients with palmar hyperhidrosis.Methods A total of 50 patients with palmar hyperhidrosis received in our hospital from August 2017 to July 2018 were selected as the research objects and divided into control group and observation group by random number table method,with 25 cases in each group.Both groups were given general anesthesia with laryngeal mask,while the control group and observation group were given Remifentanil and Dexmedetomidine respectively.The clinical related indexes,anesthesia effect,visual analogue scale(VAS)and hospitalization time of the two groups were compared.Results The heart rate of patients in the observation group was slower than that in the control group at 15 minutes after commencement of surgery and at post-surgical 30 minutes,with statistically significant difference(P<0.05).The respiratory frequency of patients in the observation group was higher than that in the control group at 15 minutes and 30 minutes after commencement of surgery,with statistically significant difference(P<0.05).The end-tidal partial pressure of carbon dioxide of patients in the observation group was lower than that of the control group at 15 minutes and 30 minutes after commencement of surgery,with statistically significant difference(P<0.05).The mean arterial pressure of the observation group was lower than that of the control group at 15 and 30 minutes after commencement of surgery as well as at post-surgical 30 minutes,with statistically significant difference(P<0.05).There was no statistically significant difference in oxygen saturation of blood at different time points compared between the two groups(P>0.05).The autonomous recovery time,extubation time,total recovery time and hospitalization time of the observation group were shorter than those of the control group,with statistically significant difference(P<0.05).The VAS score of the observation group was lower than that of the control group,with statistically significant

关 键 词：手汗症 胸腔镜交感神经链切除术 喉罩全身麻醉 右美托咪定 瑞芬太尼 

分 类 号：R614[医药卫生—麻醉学]