肌肉减少症与慢性阻塞性肺疾病关系的研究进展  

The recent research progress on relationship between sarcopenia and chronic obstructive pulmonary disease

作　　者：刘钟桧 张晓琳[1] 刘新民[1] Liu Zhonghui;Zhang Xiaolin;Liu Xinmin(Department of Geriatrics,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院老年病内科,100034

出　　处：《中华老年医学杂志》2019年第8期945-948,共4页Chinese Journal of Geriatrics

摘　　要：肌肉减少症(肌少症)是以骨骼肌质量下降和功能减退为特点的老年综合征,可导致老年人跌倒、伤残风险显著增加。慢性阻塞性肺疾病(COPD)患者更易罹患肌少症,同时肌少症也可能加剧COPD患者肺功能的恶化。探索COPD合并肌少症的机制和两者的关系有助于深入理解COPD表型、优化个体化治疗和管理。应在老年COPD患者中积极开展肌少症的筛查,进行早期干预,改善疾病预后。Sarcopenia is a complicated geriatric syndrome characterized by the loss of skeletal muscle mass and skeletal muscle dysfunction, which can lead to a significant increase in the risk of falls and disabilities in the elderly.Patients with chronic obstructive pulmonary disease(COPD)are more likely to suffer from sarcopenia, which may aggravate the deterioration degree of lung function.Exploring the mechanism and relationship of COPD with sarcopenia is helpful to understand the phenotype of COPD and to optimize a personalized treatment and management.Sarcopenia should be actively screened and intervened as early as possible to improve the prognosis of the elderly COPD patients.

关 键 词：肌少症 肺疾病 慢性阻塞性 

分 类 号：R563.9[医药卫生—呼吸系统] R685[医药卫生—内科学]