皮损内注射曲安奈德联合CO2点阵激光治疗增生性瘢痕  

Intradermic Injection Triamcinolone Acetonide Combined with CO2 Dot Array Laser in the Treatment of Hypertrophic Scar1112

作　　者：伍星蓉 周平华[1] 吴志强[1] 廖阳英[2] WU Xing-rong;ZHOU Ping-hua;WU Zhi-qiang;LIAO Yang-ying(Department of Dermatology,Changsha No.4 Hospital,Changsha 410006,Hunan,China;Department of Dermatology,HunanProvincial People's Hospital,Changsha 410006,Hunan,China)

机构地区：[1]长沙市第四医院皮肤科,湖南长沙410006 [2]湖南省人民医院皮肤科,湖南长沙410006

出　　处：《中国美容医学》2019年第9期32-34,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨皮损内注射曲安奈德联合CO2点阵激光治疗增生性瘢痕的临床效果。方法:选取2016年3月-2018年3月于长沙市第四医院皮肤科治疗增生性瘢痕患者220例,随机分为观察组(112例)和对照组(108例)。对照组给予皮损内注射曲安奈德治疗,观察组在对照组治疗基础上联合CO2点阵激光治疗,观察两组治疗后的临床效果。结果:观察组临床治疗总有效率明显高于对照组(χ^2=12.06,P<0.01),观察组瘢痕厚度明显低于对照组(P<0.05),观察组温哥华瘢痕标度法(VSS)评分明显优于对照组(P<0.01),观察组皮肤萎缩、毛囊炎、色素沉着、创面溃疡等不良反应发生率也明显低于对照组(χ^2=5.79,P<0.05)。结论:皮内注射曲安奈德联合CO2点阵激光治疗增生性瘢痕,能显著降低瘢痕厚度,改善VSS评分,降低不良反应,提高临床疗效,值得在临床上推广使用。Objective To investigate the clinical effect of intradermic injection of triamcinolone acetonide in combination with CO2 dot matrix laser in the treatment of hypertrophic scar. Methods 220 patients with hypertrophic scar who visited Changsha No.4 Hospital for treatment from March 2016 to March 2018 were selected and randomly divided into the observation group(112 cases) and the control group(108 cases). The control group was treated with intradermic injection triamcinolone acetonide into the skin lesion, and the observation group was treated with CO2 lattice laser on the basis of the control group. The clinical effect of the two groups after treatment was observed. Results Clinical total effective observation group was obviously higher than that of control group(χ^2=12.06,P<0.01), the scar thickness of observation group was obviously lower than the control group(P<0.05), the observation group vancouver scar(VSS) rating scale method is superior to the control group(P<0.01), the observation group of skin atrophy, folliculitis, pigmentation, the incidence of adverse reactions such as wound ulcer is significantly lower than the control group(χ^2=5.79,P<0.05). Conclusion Intradermal injection of triamcinolone acetonide combined with CO2 dot matrix laser can significantly reduce scar thickness and improve VSS score, reduce adverse reactions and improve clinical efficacy, which is worthy of clinical application.

关 键 词：曲安奈德 皮内注射 CO2点阵激光 增生性瘢痕 瘢痕厚度 疗效 

分 类 号：R619.6[医药卫生—外科学]