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作 者:沈鸿[1] 穆兰澄[2] 汪芳[1] 谢利民[2] Shen Hong;Mu Lancheng;Wang Fang;Xie Limin(Institute of Chinese Materia Medica,China Academy of Chinese Medicinal Sciences,Beijing 100700,China;Guang′anmen Hospital,China Acabemy of Chinese Medical Sciences,Beijing 100053,China)
机构地区:[1]中国中医科学院中药研究所,北京100700 [2]中国中医科学院广安门医院,北京100053
出 处:《世界中医药》2019年第8期2042-2047,共6页World Chinese Medicine
基 金:北京市科学技术委员会资助(“十病十药”项目Z161100001816017)
摘 要:目的:基于文献调查了近20年内羌活的临床应用情况,分析探讨羌活的用药特点,展示羌活的用药现状,为羌活的临床应用提供参考。方法:采用计算机检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、万方数据库中有关以羌活为主药的临床研究文献,检索时间范围1997年1月至2017年12月,筛选符合纳入标准的随机、半随机或有较好临床疗效的临床研究文献。从与配伍药物频次的多少、主要的主治疾病、主治证候等方面进行计量学分析、总结。结果:与羌活配伍应用的药物,出现频次前三位的是:川芎、防风、甘草;主治疾病前三位的是颈椎病、膝骨关节炎、偏头痛;主治证候前三位的是风寒湿邪、痹阻经脉、气血不畅。结论:羌活以配伍活血药和祛风止痛药为主,治疗各类颈椎病、膝骨关节炎、偏头痛等为主,多用于寒痹疼痛、气血瘀阻之证。Objective: To explore the clinical application of Rhizoma et Radix Notopterygii based on the literature in the last 20 years,to analyze and discuss the medication characteristics of Rhizoma et Radix Notopterygii,to present the medication situation of Rhizoma et Radix Notopterygii,and to provide reference for the clinical application of Rhizoma et Radix Notopterygii. Methods: Clinical research literature taken Rhizoma et Radix Notopterygii as the main medicine in the China National Knowledge Infrastructure(CNKI),China Science and Technology Journal Database(VIP)and Wanfang was retrieved by computer,and the retrieval time was from January 1997 to December 2017.Clinical research literature,which was about randomized trials,half-randomized trials or trails with good clinical efficacy were screened and included.From the aspects like compatibility frequency,main diseases of indications,syndromes of indications,etc,metrological analysis and summary was performed. Results: The top 3 frequently used medicines compatible with Rhizoma et Radix Notopterygii were:Rhizoma Chuanxiong,Radix Saposhnikoviae and Radix et Rhizoma Glycyrrhizae.The diseases of indications in the top 3 were:cervical spondylosis,knee osteoarthritis and migraine.The syndromes of indications in the top 3 were:wind,cold and dampness evils,meridians being blocked as well as inhibited qi and blood. Conclusion: Rhizoma et Radix Notopterygii is mainly compatible with medicines of activating blood as well as dispelling wind and relieving pain;it is mainly used in the treatment of cervical spondylosis,knee osteoarthritis and migraine;and it is mainly used in the syndromes of pain due to cold impediment and qi-blood being blocked.
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