中药及药膳辅助西药治疗类风湿关节炎的疗效及对患者营养状况的影响  

Efficacy of Western medicine assisted with traditional Chinese medicine and medicated diet on rheumatoid arthritis and its effect on patients′ nutritional status

作　　者：盛正和[1] 韦少雪[1] 刘溯章[1] 曾健[1] 朱媛月[1] 刘芙蓉[1] 翁映虹[1] 樊兰艳[1] 张剑飞[1] SHENG Zhenghe;WEI Shaoxue;LIU Suzhang;ZENG Jian;ZHU Yuanyue;LIU Furong;WENG Yinghong;FAN Lanyan;ZHANG Jianfei(Liuzhou General Hospital,Liuzhou 545006,Guangxi,China)

机构地区：[1]柳州市人民医院

出　　处：《内科》2019年第4期400-403,413,共5页Internal Medicine

基　　金：广西柳州市科技局科技攻关项目(2015J030522)

摘　　要：目的探讨中药及药膳辅助西药治疗类风湿关节炎(RA)的疗效以及对患者营养状况的影响。方法选取2015年1月至2017年12月广西柳州市人民医院中医风湿科收治的类风湿关节炎患者90例为研究对象,采用随机数字表法分为中药辅助组(30例)、药膳辅助组(30例)、单纯西药组(30例),分别给予中药+西药、药膳+西药、单纯西药治疗12周。比较三组患者的疗效、疾病活动分数(DAS)、营养学指标。结果治疗12周,中药辅助组以及药膳辅助组患者的治疗总有效率均显著高于单纯西药组(P<0.05);中药辅助组及药膳辅助组患者的DAS显著低于单纯西药组(P<0.05);中药辅助组及药膳辅助组患者的体质量指数均显著低于单纯西药组(P<0.05);药膳辅助组患者的体质量指数、三头肌皮褶厚度均显著减小;中药辅助组患者的血红蛋白水平显著升高且显著高于单纯西药组,药膳辅助组患者的血清白蛋白水平显著升高且显著高于单纯西药组,差异有统计学意义(P<0.05)。结论中药及药膳辅助西药治疗,可以显著提高类风湿关节炎患者的疗效,明显降低疾病活动分数,改善患者症状和体征,改善患者的营养状况。Objective To explore the efficacy of Western medicine assisted with traditional Chinese medicine and medicated diet on rheumatoid arthritis (RA) and its effect on patients′ nutritional status.Methods A total of 90 cases of rheumatoid arthritis patients admitted to Rheumatism Department of Traditional Chinese Medicine in Liuzhou General Hospital of Guangxi from January 2015 to December 2017 were selected as the study objects,and randomly divided into traditional Chinese medicine-assisted group (30 cases),with traditional Chinese medicine combined with Western medicine treatment,medicated diet-assisted group (30 cases),with medicated diet combined with Western medicine treatment,and Western medicine group (30 cases),with Western medicine treatment only.The course of treatment in the three groups was 12 weeks.The efficacy,disease activity score (DAS),and nutritional indicators were compared between the three groups.Results After 12 weeks of treatment,in comparison with the Western medicine group,the traditional Chinese medicine- assisted group and the medicated diet-assisted group had a higher total effective rate,a lower DAS,and a lower body mass index ( P <0.05).The body mass index and the thickness of triceps skin fold in the medicated diet-assisted group were significantly reduced.The hemoglobin level of the traditional Chinese medicine-assisted group was significantly elevated,and higher than the Western medicine group,whereas the serum albumin level of the medicated diet-assisted group was significantly increased,and higher than the Western medicine group,with statistically significant difference ( P <0.05).Conclusion Western medicine assisted with traditional Chinese medicine and medicated diet in the treatment of patients with rheumatoid arthritis can significantly improve the therapeutic effect,reduce the disease activity score,improve the patients′ symptoms,signs and nutritional status.

关 键 词：类风湿关节炎 中药 药膳 营养状况 疗效 

分 类 号：R593.22[医药卫生—内科学]