广汉市某医院新生儿院内感染现状调查分析  

Investigation and analysis of nosocomial infection of newborns in a hospital of Guanghan City

作　　者：李小英[1] 张小英[1] LI Xiao-ying;ZHANG Xiao-ying(Department of Obstetrics and Gynecology,Guanghan People’s Hospital,618300,China)

机构地区：[1]广汉市人民医院妇产科

出　　处：《传染病信息》2019年第4期333-335,共3页Infectious Disease Information

基　　金：四川省卫生厅科研课题(150855)

摘　　要：目的探讨广汉市某医院新生儿院内感染现状及影响因素。方法选取2016年9月—2017年11月广汉市人民医院出生的新生儿964例作为研究对象,收集新生儿各项临床资料并进行回顾性分析,计算新生儿院内感染率,采用多元Logistic回归分析影响新生儿院内感染的独立危险因素。结果964例新生儿中,41例新生儿发生院内感染,感染率为4.25%。感染部位中以呼吸系统感染多见,共25例(60.97%),其次为血液感染9例(21.95%),皮肤感染7例(17.07%)。细菌培养结果显示革兰阴性杆菌共25株(60.97%),其中大肠埃希菌14株(34.14%),肺炎克雷伯菌11株(26.82%);革兰阳性球菌共14株(34.14%),其中金黄色葡萄球菌4株(9.75%),肠球菌属8株(19.51%);真菌2株(4.87%)。单因素分析发现胎龄、体质量、Apgar评分、使用呼吸机、侵入性操作、住院时间>1周均是影响新生儿院内感染的因素,差异具有统计学意义(P均<0.05);进一步经多元Logistic分析结果显示:体质量(<2.5kg)、Apgar评分(<5分)、使用呼吸机、侵入性操作、住院时间>1周均是影响新生儿院内感染的独立危险因素,差异具有统计学意义(P均<0.05),胎龄并非是影响新生儿院内感染的独立危险因素(P>0.05)。结论新生儿仍然有一定几率发生院内感染,体质量、Apgar评分、使用呼吸机、侵入性操作、住院时间是影响院内感染发生的独立危险因素。Objective To explore the current situation and influencing factors of neonatal nosocomial infection in a hospital of Guanghan City.Methods Nine hundred and sixty-four neonates born in Guanghan People’s Hospital from September 2016 to November 2017 were selected.The clinical data of neonates were collected and analyzed retrospectively.The incidence of nosocomial infection in neonates was calculated.The independent risk factors affecting neonatal nosocomial infection were analyzed by multivariate Logistic regression.Results In 964 neonates,41 had nosocomial infection,the incidence of infection was 4.25%.Respiratory infection was the most common type of infection,accounting for 25 cases(60.97%),followed by blood infection in 9 cases(21.95%)and skin infection in 7 cases(17.07%).The results of bacterial culture showed that there were 25 Gram-negative bacilli(60.97%),including 14 strains of Escherichia coli(34.14%)and 11 strains of Klebsiella pneumoniae(26.82%),14 strains of Gram-positive cocci(34.14%),including 4 strains of Staphylococcus aureus(9.75%)and 8 strains of Enterococcus(19.51%);and 2 strains of fungi(4.87%).Gestational age,body mass,Apgar score,use of ventilator,invasive operation,hospitalization stay>1 week were single factors affecting neonatal nosocomial infection,the difference was statistically significant(P<0.05).Multivariate Logistic analysis showed that body mass(<2.5 kg),Apgar score(<5 points),use of ventilator,invasive operation and hospitalization stay>1 week were independent risk factors affecting neonatal nosocomial infection and the difference was statistically significant(P<0.05).Gestational age was not an independent risk factor affecting neonatal nosocomial infection(P>0.05).Conclusions Newborns still have a chance to develop nosocomial infections.Body mass,Apgar score,use of ventilator,invasive operation and hospitalization stay are the risk factors of nosocomial infection.

关 键 词：新生儿院内感染 现状 调查分析 

分 类 号：R181.3[医药卫生—流行病学]