RNA binding to p62 impacts selective autophagy  

作　　者：Mohit Misra Ivan Dikic 

机构地区：[1]Institute of Biochemistry II, Goethe University - Medical Faculty, University Hospital Frankfurt, Theodor-Stern-Kai 7, Frankfurt am Main 60590, Germany [2]Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Riedberg Campus, Max-von-Laue-StraBe 15, Frankfurt am Main 60438, Germany

出　　处：《Cell Research》2019年第7期512-513,共2页细胞研究（英文版）

摘　　要：Role of RNA regulation in autophagy was rather unexplored until Horos et al. recently showed that vault RNA1-1 binds directly to p62/SQSTM1, a well-established autophagy receptor. This binding leads to inhibition of p62 oligomerization and negative regulation of selective autophagy pathways.

关 键 词：RNA rather pathways 

分 类 号：Q[生物学]