ASS评分、CRP、S100β变化对胸部外伤患者早期感染的预测价值  

Predictive value of ASS,CRP and S100β changes for early infection of patients with chest trauma

作　　者：李勇强[1] 孙志红[1] LI Yongqiang;SUN Zhihong(Department of Thoracic Surgery,Second Affiliated Hospital of Xi'an Medical College,Xi'an,Shaanxi 710038,China)

机构地区：[1]西安医学院第二附属医院胸外科

出　　处：《检验医学与临床》2019年第17期2475-2477,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨全身炎症反应综合征修正(ASS)评分、C反应蛋白(CRP)、S100β变化对胸部外伤患者早期感染的预测价值。方法将该院收治的89例胸部外伤患者作为研究对象,根据其是否发生早期感染分为感染组33例和无感染组56例,两组患者均于入院1周内进行ASS评分,并在入院1、3、7、10、14d时测定其血浆CRP、血清S100β和外周血白细胞计数(WBC)水平。结果感染组ASS评分高于无感染组(P<0.05);感染组患者入院1、3、7d血浆CRP和血清S100β水平均高于无感染组(P<0.05),入院1、3、7、10、14dWBC水平均高于无感染组(P<0.05)。结论胸部外伤患者入院后ASS评分可有效预测早期感染,CRP、S100β变化对患者早期感染诊断具有指示作用。Objective To investigate the predictive value of adjusted score of systemic inflammatory response syndrome(ASS),C-reactive protein(CRP)and S100βchanges for early infection of patients with chest trauma.Methods A total of 89 patients with chest trauma admitted to the hospital were enrolled.According to the presence or absence of early infection,they were divided into infection group(33 cases)and non-infection group(56 cases).Both groups underwent ASS scoring within 1 week after admission.The levels of plasma CRP,serum S100βand peripheral blood leukocyte(WBC)were measured at 1 d,3 d,7 d,10 d and 14 d after admission.Results The scoring of ASS in the infection group were significantly higher than those in the non-infection group(P<0.05).The levels of plasma CRP and serum S100βin the infection group were higher than those in the non-infection group at 1 d,3 d,and 7 d after admission(P<0.05).1 d,3 d,7 d after admission.The WBC levels at 1 d,3 d,7 d,10 d and 14 d after admission were higher than those in the non-infection group(P<0.05).Conclusion ASS scoring in patients with chest trauma can effectively predict early infection after admission.CRP and S100βchanges have an indication role for early infection diagnosis.

关 键 词：胸部外伤 全身炎症反应综合征 C反应蛋白 S100Β 早期感染 

分 类 号：R655[医药卫生—外科学]