激光辅助孵化对玻璃化冷冻的卵裂期胚胎妊娠结局的影响  

Effect of laser-assisted incubation on pregnancy outcome of vitrectomy in cleavage stage embryos

作　　者：史鸿志 秦妍 张楠 宋琪 李伟伟 殷秀荣 SHI Hongzhi;QIN Yan;ZHANG Nan;SONG Qi;LI Wei-wei;YIN Xiu-rong(Hebei Qinhuangdao Maternal and Child Health Care Hospital,Hebei Qinhuangdao 066000)

机构地区：[1]河北省秦皇岛市妇幼保健院

出　　处：《中国优生与遗传杂志》2019年第8期1000-1001,1006,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨激光辅助孵化(LAH)对玻璃化冷冻的卵裂期胚胎妊娠结局的影响。方法回顾性分析2017~2018年198个卵裂期胚胎解冻移植周期,其中行激光辅助孵化(LAH)64个周期,未进行激光辅助孵化(NLAH)134个周期。结果 LAH组的临床妊娠率和胚胎种植率均低于NLAH组,而多胎率和流产率均高于NLAH组,但差异没有统计学意义(P>0.05)。结论激光辅助孵化对于玻璃化冷冻的卵裂期胚胎的妊娠结局没有明确的作用。Objective:To investigate the effect of laser assisted hatching(LAH)on the pregnancy outcome of vitrified cleavage embryos. Methods:A retrospective analysis was performed on the date of 198 circles that thawed cleavage embryo transfer,including 64 cycles were LAH,and 134 cycles without laser assisted hatching(NLAH). Results:The clinical pregnancy rate and embryo implantation rate in the LAH group were lower than those in the NLAH group,and the multiple birth rate and abortion rate were higher than those in the NLAH group,but the difference was not statistically significant(P>0.05). Conclusion:Laser-assisted incubation has no definitive effect on the pregnancy outcome of vitrified cleavage embryos.

关 键 词：激光辅助孵化 玻璃化冷冻 卵裂期胚胎 临床妊娠 

分 类 号：R321-33[医药卫生—人体解剖和组织胚胎学]