打破碗花花化学成分研究  

Study on Chemical Constituents of Anemone Hupehensis Lem.

作　　者：刘雨 田从魁 朱婷婷 李月菲 LIU Yu;TIAN Congkui;ZHU Tingting;LI Yuefei(Hubei Provincial Key Laboratory of Occurrence and Intervention of Rhumatic Diseases (Hubei Minzu University),Enshi 445000,China;Wuling Mountain Institute of Natural Medicine,Hubei Minzu University,Enshi 445000,China;Key Laboratory of Biological Resources Protection and Utilization of Hubei Province (Hubei Minzu University),Enshi 445000,China;Shenzhen Academy of Environmental Sciences,Shenzhen 518001,China)

机构地区：[1]风湿性疾病发生与干预湖北省重点实验室(湖北民族大学),湖北恩施445000 [2]湖北民族大学武陵山天然药物研究所,湖北恩施445000 [3]生物资源保护与利用湖北省重点实验室(湖北民族大学),湖北恩施445000 [4]深圳市环境科学研究院,广东深圳518001

出　　处：《湖北民族学院学报（自然科学版）》2019年第3期249-253,共5页Journal of Hubei Minzu University(Natural Science Edition)

基　　金：国家自然科学基金项目(81860613);风湿性疾病发生与干预湖北省重点实验室项目(OIR15003);湖北民族学院博士启动基金项目(MY2015B004);生物资源保护与利用湖北省重点实验室重点项目(PKLHB1504)

摘　　要：采用硅胶、SephadexLH-20、制备液相等色谱方法对打破碗花花70%乙醇提取液进行分离纯化,运用理化性质和核磁共振波谱、质谱等数据进行结构鉴定.结果得到了15个化合物,分别鉴定为:棕榈酸(1)、4-甲氧基水杨醛(2)、邻苯二甲酸二甲酯(3)、苯甲酸(4)、桂皮酸(5)、3-(4′-formylphenoxy)-4-methoxybenzaldehyde(6)、eugenin(7)、滨蒿内酯(8)、7-甲氧基香豆素(9)、1,8-二羟基蒽醌(10)、咖啡酸甲酯(11)、齐墩果酸(12)、阿魏酸(13)、咖啡酸(14)、胸腺嘧啶核苷(15).化合物2~4、6~11为首次从银莲花属植物中分离得到,所有化合物均是首次从打破碗花花中分离得到.The constituents were isolated and purified by silica,Sephadex LH-20,and preparative HPLC.The structures were elucidated on the basis of spectroscopic data and chemical derivatization method.Fifteen constituents were isolated from the plant and identified as palmitic acid(1),4-methoxysalicy-laldehyde(2),dimethyl phthalate(3),benzoic acid(4),cinnamic acid(5),3-(4′-formylphenoxy)-4-methoxybenzaldehyde(6),eugenin(7),scoparone(8),7-methoxycoumarin(9),1,8-dihydroxyanthraquinone(10),methylcaffeate(11),oleanic acid(12),ferulicacid(13),caffeic acid(14),thymine deoxyribose(15).Compound 2~4,6~11 were isolated from Amenone, and all the compounds were isolated from Amenone hupehensis for the first time.

关 键 词：打破碗花花 化学成分 结构鉴定 

分 类 号：R285[医药卫生—中药学]