光动力治疗老年性皮肤肿瘤应用及研究进展  

Progress in Photodynamic Therapy for the Senile Skin Tumors

作　　者：张海艳[1] 王佩茹 王秀丽[1] ZHANG Haiyan;WANG Peiru;WANG Xiuli(Institute of Photomedicine,Shanghai Skin Disease Hospital,Tongji University School of Medicine,Shanghai 200443,China)

机构地区：[1]上海市皮肤病医院光医学治疗科同济大学医学院光医学研究所

出　　处：《皮肤科学通报》2019年第4期503-507,8,9,共7页Dermatology Bulletin

基　　金：国家自然科学基金面上项目(81872212);上海市2017年度“科技创新行动计划”临床医学领域项目(17411952500)

摘　　要：皮肤肿瘤好发于老年人,其中较为常见的是非黑色素瘤皮肤癌(nonmelanoma skin cancer,NMSC)。光动力疗法近乎无创不损伤其他功能器官,对老年皮肤肿瘤具有安全、可重复、无耐药等优势。光动力疗法通过直接杀伤肿瘤及脉管系统、诱导抗瘤免疫等机制治疗皮肤肿瘤,临床上光动力治疗皮肤NMSC尤其是浅表性肿瘤疗效确切,亦可用于老年皮肤肿瘤预防、联合辅助治疗及姑息治疗。本文就光动力疗法治疗NMSC的现有研究成果进行综述。Skin tumors tend to occur in the elderly,the most common of which is non-melanoma skin cancer (NMSC).Photodynamic therapy (PDT) is an emerging non-invasive method for skin tumors.Numerous clinical studies have confirmed that PDT can effectively treat NMSC without any other organ function damage.This article reviews the progress in photodynamic therapy for the skin tumors in the elderly.

关 键 词：皮肤肿瘤 非黑色素瘤性皮肤癌 光动力疗法 

分 类 号：R592[医药卫生—老年医学] R739.5[医药卫生—内科学]